545. New metabolites of Gibberella fujikuroi. Part II. The isolation of fourteen new metabolites

Abstract

Extracts from culture filtrates of Gibberella fujikuroi grown under various fermentation conditions have yielded the following metabolites : 7-hydroxy-,

New Metabolites, 2,4,6-Triketosuberic Acid and 2,4,6,8-Tetraketosebacic Acid, Formed from 2-Butyne-1,4-diol byFusarium merismoidesB11

“…Namely, the UV maximum was seen at 275 nm (s=490) and the IR spectrum showed strong bands at 1735 (COOMe) and 1715 cm-1 (-CO-) in CHCI 3 . Four singlet were seen in the NMR spectrum at 3.05 (2H), 3.29 (2H x 3), 3.68 (3H) and 3.82 ppm (3H) (Fig. 3).…”

Metabolism of the Aromatic Amino Acids by Fungi

“…1.3, R=H). This alcohol has also been isolated from Torulopsis versatilis (A)9, species of Candida (A)97,126 and other yeasts (A)175 when phenylalanine was added to the medium and from culture filtrates of Gibberella fujikuroi (A) 41 and Ceratocystis fimbriata (A)156. It is not known whether it is derived by reduction of pheny1acetate or by deamination of phenethy1amine.…”

Gibberellin biosynthesis inGibberella

“…The main carotenoid accumulated by Gibberella is neurosporaxanthin, an acidic xantophyll responsible for the pale orange colour of the fungus when grown in the light or the deep orange colour of deregulated mutant strains (Avalos & Cerda-Olmedo, 1987). Other terpenoids in Gibberella include cyclonerodiol (Cross eta/., 1971 ), derived from famesyl pyrophosphate, and kaurenolides (Beale eta/., 1982), fujenal (Cross et a/., 1963;A lam et a/., 1991 ), and gibelactol (Barrero et a/., 1992), derived from various intermediates of the specific section of the gibberellin pathway.…”