3α-Hydroxy-lup-20(29)-ene-23,28-dioic acid from Schefflera octophylla

Triterpene Glycosides and Glucosyl Esters, and a Triterpene from the Leaves of Schefflera actinophylla

“…The carbon signal at C-3 was shifted downfield than that of the free aglycone in literature, 2) indicating its glucosylation at this position. This was confirmed from the analysis of HMBC spectrum that showed correlation cross peak between H-1Ј of the glucose moiety with C-3 of the aglycone at (d C 79.9).…”

“…The methanolic layer was evaporated, suspended in water and then extracted with EtOAc and 1-BuOH, successively. The 1-BuOH-soluble fraction as well as the EtOAc-soluble fraction was subjected to Diaion HP-20, silica gel, octadecylsilanized (ODS) silica gel column chromatographies (CC), droplet counter-current chromatography (DCCC), and high-performance liquid column chromatography (HPLC) to afford seven new compounds (1)(2)(3)(4)(5)(6)(7), along with nine known triterpene compounds, 3a-hydroxylup-20(29)-ene-23,28-dioic acid (8), 2) …”

Lupane Glycosides from the Leaves of Acanthopanax koreanum

“…The assignment of the ahydroxyl group at C-3 was performed by comparing spectral data to literature values. [14][15][16] In the NOESY spectrum, the presence of cross-peaks between H-24 and H-25 as well as H-3 indicated that the methyl group (H-24) was axial, which in turn suggested that the carboxyl group at C-4 was a-positioned. In the HMBC spectrum, the carbonyl carbon signal at d 175.1 (C-28) showed a The three isolates (1-3) were assessed for anti-inflammatory activity by examining their effects on nitric oxide (NO) and prostaglandin E 2 (PGE 2 ) by lipopolysaccharide (LPS)-induced in RAW 264.7 cells.…”

Triterpenoids

“…12 of 'Terpenoids and Steroids', p. 223), Grieco and his coworkers have now employed the intermediate (83) to elaborate a notable total synthesis of dl-castelanolide (84). 62 In an alternative synthetic approach, thermolysis of the dl-benzocyclobutene (85) gave the tetracyclic compound (86), which was further transformed into the lactone (87).…”