Acanthopanax genus is a shrub indigenous to Northeast Asia. Its bark, known as Acanthopanis Cortex, is used to treat sinew and bone pains in traditional oriental medicine. Several studies on the triterpenoid constituents of Acanthopanax koreanum NAKAI, have been reported. [1][2][3] As a results of an in-going search for the phytochemical constituents in Acanthopanax genus, [4][5][6][7][8][9] we report on the isolation of a new lupane triterpene glycoside, acankoreosideester from the leaves of Acanthopanax koreanum and describe the determination of its structure.The methanolic extract of A. koreanum leaves gave acankoreoside E (1) by the various chromatographic techniques. Acankoreoside E (1) was obtained as a white amorphous powder of molecular formula C 48 H 76 O 20 , as determined by HR-FAB-MS (molecular ion peak at m/z 995.4828 due to [MϩNa] ϩ ). Its 13 C-NMR and DEPT spectra revealed 48 carbons signals, 30 of which were assigned to a triterpenoid sapogenol moiety, and 18 to three monosaccharide moieties. Relevant 1 H-NMR data showed the following; four tertiary methyl groups [d 0.85, 0.96, 1.19
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.