3D Reconstruction Role in Surgical Treatment of Sinonasal Tumours

Abstract

Three-dimensional printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients. Nowadays, 3D printing is very well integrated in the surgical practice and research. Also, the field of head and neck reconstructive surgery is constantly evolving because of the three-dimensional printing, a technology which can be widely used in a variety of situations such as reconstruction of tissue defects, surgical planning, medical modeling and prosthesis. By using 3D printing into tissue engineering and materials, it may be possible for otolaryngologists to implant 3D printed functional grafts into patients and will also provide a rapid production of personalized patient-specific devices. Advances in 3D printed implants and future tissue-engineered constructs will bring great progress to the field of otorhinolaryngology.

The TAC and MDA Values in Patients with Chronic Suppurative Otitis Media

“…In our study, the MDA levels in the patients group with CSOM with and without cholesteatoma and cholesteatoma recidivism were higher compared to the healthy group, which reflect an increased lipid peroxidation, a result similar to a 2015 study [22]. According to Holecek et al,lipoperoxidation may be a marker of disease severity in otitis media,being involved in many other otorhinolaryngological diseases [23][24][25]. Increased MDA values determined in serum and in the middle ear mucosa were found in albino rabbits, with a correlation between results, thus reflecting the tissue damage caused by otitis [26][27][28].…”

Multimodality Approach to Treatment of Rhinosinusal Tumours

“…Modern treatment of a neoplasm should be considered as a therapeutic protocol (multimodal treatment) established by a complex team (surgeon, radiologist, oncologist, etc.) where each treatment method (chemotherapy, surgery, radiotherapy, hormone therapy, bone marrow transplantation) have to find their place based on various factors and their chronology [16][17][18].…”

Biological Chemistry in Intermediate Lipid Metabolism Disorder

“…Atherosclerosis is linked to the cholesterol metabolism disorder. This condition consists in the thickening of the inner layer of the vascular walls, especially in the large arteries, and in the depositing in this layer of lipoid substances (cholesterol and its esters) [10].…”

“…In the pathogenesis of atherosclerosis, the modification of the vascular wall is important, a fact due to poisoning or haemodynamic disorders [9][10][11][12].…”