3D printed extended release tablets for once daily use: An in vitro and in vivo evaluation study for a personalized solid dosage form

3D printing of pharmaceutical oral solid dosage forms by fused deposition: The enhancement of printability using plasticised HPMCAS

“…Compared to large-scale dosage form production, FDM-3DP follows a new paradigm (Rayna and Striukova, 2021). Unlike conventional manufacturing techniques, FDM-3DP permits on-demand tablet production with tailored dose and drug release patterns avoiding stock storage and material wastage (Khaled, Alexander et al, 2018;Park, Choi et al, 2018;Thakkar, Pillai et al, 2020;Gultekin, Tort et al, 2021;Krause, Müller et al, 2021). FDM-3DP also allows lifecycle management opportunities to prolong the intellectual ownership of innovative products in the period of exclusivity loss (FierceMarkets, 2021).…”