3D Powder Printing of β‐Tricalcium Phosphate Ceramics Using Different Strategies

Vorndran, Elke; Klarner, Mara; Klammert, Uwe; Grover, Liam M.; Patel, Sarika; Barralet, Jake E.; Gbureck, Uwe

doi:10.1002/adem.200800179

Cited by 157 publications

(102 citation statements)

References 24 publications

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“…Compared to that, the immersion in 7.5 wt.% LA showed a lower coverage. Literature claims a compressive strength of 3D-printed composites with other bio polymers in a range of 0.5-5 MPa [6] [7]. This emphasizes the potential of the herein investigated material with its 16.3 MPa CS.…”

Section: Discussionmentioning

confidence: 54%

3D printed chitosan / hydroxyapatite scaffolds for potential use in regenerative medicine

Chavanne

Stevanovic

Wüthrich

et al. 2013

Biomedical Engineering / Biomedizinische Technik

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Section: Discussionmentioning

confidence: 54%

3D printed chitosan / hydroxyapatite scaffolds for potential use in regenerative medicine

Chavanne

Stevanovic

Wüthrich

et al. 2013

Biomedical Engineering / Biomedizinische Technik

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“…This is not fully understand and not in agreement with previous studies which however did not show relative cell growth, thus can not be directly compared. [21,25,51,52] Cytoskeleton evaluations showed that incorporation of both fillers improved its organization. In general, for the filled samples cytoskeleton was well organized with well developed actin and tubulin networks when compared with pure polymer samples.…”

Section: Discussionmentioning

confidence: 99%

“…[17,18] Concentrating on bone tissue applications and considering polymer based materials (filled polymers and composites), hydroxyapatite, tricalcium phosphate (TCP) or Bioglass are the most popular used fillers. [16,[19][20][21][22][23][24][25][26] Other interesting materials are phosphate glasses, which have readily tuneable properties to improve cellular activity [27][28][29][30][31] or inhibit biofilm formation (antimicrobial glasses). [32][33][34] To date they were rarely used as polymer fillers.…”

mentioning

confidence: 99%

Tailoring Cell Behavior on Polymers by the Incorporation of Titanium Doped Phosphate Glass Filler

et al. 2010

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Understanding tissue response to materials, to enable modulation and guided tissue regeneration is one of the main challenges in biomaterials science. Nowadays polymers, glasses, and metals dominate as biomaterials. Often native properties of those materials are not sufficient and there is a need to combine them, so as to modify and adjust their properties to the application. The primary aim of this study was to improve cell response to polymer (PLDL) using phosphate glass as filler (titanium doped phosphate glass). As a control β‐tricalcium phosphate (TCP) filler was used. Various concentrations of the filler were used (10–40 vol%). Wetting behavior, ζ‐potentials, mechanical and thermal properties, and human cells response to the materials were evaluated. Results showed that with increase in glass filler loading wettability improved, ζ‐potentials dropped, and increase in stiffness of materials was observed. Importantly cell culture experiments showed more developed and well spread cells on the samples with glass content up to 20 vol%. Cells responded much more positively to the glass filled samples than to TCP filled. However, expression of osteocalcin and osteopontin, proteins that indicate formation of the mineralized structures was positive for all the samples including pure PLDL. It was concluded that due to improved wetting behavior, lower ζ‐potentials, and specific chemistry of the glass filler it was possible to alter cells response, improve bioactivity of the polymer, and vary mechanical properties.

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“…One of the important benefits of this method is the powder bed support by itself for each successive layer. The fragility of the obtained parts is considered a drawback [81][82][83][84][85][86][87][88].…”

Section: D Printing (3dp)mentioning

confidence: 99%

Bioceramic Scaffolds

Amin¹,

Ewais²

2017

Scaffolds in Tissue Engineering - Materials, Technologies and Clinical Applications

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Millions of peoples in the world suffer from their bone damage tissues by disease or trauma. Every day, thousands of surgical procedures are performed to replace or repair these tissues. The availability of these tissues is a big problem, and their costs are expensive. The repair of these defects has become a major clinical and socioeconomic need with the increase of aging population and social development. The emerge of tissue engineering (TE) is considered as a glimmer of hope to contribute in solving this problem. It aims at the regeneration of damaged tissues with restoring and maintaining the function of human bone tissues using the combination of cell biology, materials science, and engineering principles. In this chapter, the current state of the tissue engineering in particular bioceramic scaffolds was discussed. Concept of tissue engineering was explored. Bioceramic scaffold materials, their processing techniques, challenges taken into consideration the design of the scaffolds, and their in-vitro and in-vivo studies were highlighted. The scaffolds with extra-functionalities such as drug release ability and clinical applications were mentioned.

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3D Powder Printing of β‐Tricalcium Phosphate Ceramics Using Different Strategies

Cited by 157 publications

References 24 publications

3D printed chitosan / hydroxyapatite scaffolds for potential use in regenerative medicine

3D printed chitosan / hydroxyapatite scaffolds for potential use in regenerative medicine

Tailoring Cell Behavior on Polymers by the Incorporation of Titanium Doped Phosphate Glass Filler

Bioceramic Scaffolds

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