Three pairs of sesquiterpene enantiomers from <i>Chloranthus multistachys</i> pei

Huang, Wei‐Ming; Chen, Fang-You; Bian, Yuting; Ning, Tian-jiao; Chen, Zhichao; Shuang, Peng-Cheng; Luo, Yongming

doi:10.1080/14786419.2021.1929974

Cited by 4 publications

(1 citation statement)

References 22 publications

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“…In addition, twelve known sesquiterpenes (1 β ,4 α ,6 β )‐gorgonane‐1 β ,4 α ,11‐triol ( 6 ), [17] 4(15)‐eudesmene‐1 β ,7,11‐triol ( 7 ), [18] 3‐eudesmene‐1 β ,7,11‐triol ( 8 ), [18] (4 α ,7 β ,9 α )‐farfugane‐4,9,11‐triol ( 9 ), [17] (4 α ,7 α ,9 α )‐farfugane‐4,9,11‐triol ( 10 ), [17] 4,10,11‐trihydroxyguaiane ( 11 ), [19] atractylenolid III ( 12 ), [20] 8 β ‐methoxyatractylenolide ( 13 ), [21] 8 β ,9 α ‐dihydroxyeudesma‐4(15),7(11)‐dien‐8 α ,12‐olide ( 14 ), [22] atractylenolide I ( 15 ), [23] hinesolone ( 16 ), [24] macrochaetoside B ( 17 ) [25] were identified ( Figure S6 ). 13 C‐NMR data of these compounds were summarized in Table S1 .…”

Section: Resultsmentioning

confidence: 99%

Cytotoxic Sesquiterpenoids from Atractylodes chinensis (DC.) Koidz.

Zhuang

Liu

Wang

et al. 2022

Chemistry & Biodiversity

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Four new sesquiterpenoids named atrchiterpenes A–D (1–4), a new natural product (5), and twelve known compounds (6–17) were isolated from Atractylodes chinensis (DC.) Koidz. Compound 1 was a rare N‐containing eudesmane‐type sesquiterpenoid. Structure elucidation was performed by spectroscopic techniques, including 1D, 2D NMR spectra, and HR‐ESI‐MS. Compounds 6–11, 14, and 17 were reported from Atractylodes for the first time. All the isolated compounds were evaluated for cytotoxicity activity. Compound 16 showed moderate cytotoxicity against HepG2 cells with an IC50 value of 5.81±0.47.

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