COVID-19 and global mental health

Ardila-Gómez, Sara; Díaz, Alex Mauricio; Vargas, Elena Cachicatari; Trujillo, María Adelaida Arboleda; Ortega, Edison Javier Cárdenas; Agrest, Martín

doi:10.1016/s2215-0366(21)00150-4

Cited by 4 publications

(3 citation statements)

References 1 publication

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“…While COVID-19 itself can lead to psychiatric sequelae and neurological damage, including PTSD, anxiety, depression, motor dysfunction (1, 16, 21-23, 26, 27), cognitive impairment (13,14) and ischaemic brain injury (11,150,167), related socioeconomic stressors and unhealthy lifestyles may increase the risk of mental disorders (7,11,24,27), such as anxiety, depression, PD, AD, and ischaemic stroke, in the general population (3,26). The current evidence suggests that salidroside can ameliorate the exacerbation of psychiatric sequelae and brain injuries via multiple pathways and combat the negative effects of stressors (…”

Section: Conclusion and Remarksmentioning

confidence: 99%

“…In addition, pathological factors that can cause physical sequelae (11,13,18,23) may persist in the human body after recovery from COVID-19 (23)(24)(25)(26). Current clinical evidence (11,(25)(26)(27) suggests that these pathological factors can lead to damage to the brain and nervous system (3,14,24,25) and potentially to the development of mental disorders, such as anxiety, depression and PTSD, and brain injuries (21,24,26,27). Therefore, COVID-19 itself as well as its associated psychiatric complications are severe public health challenges worldwide that further increase medical costs and contribute to the public mental health crisis (20)(21)(22).…”

Section: Introductionmentioning

confidence: 99%

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Brain Network Homeostasis and Plasticity of Salidroside for Achieving Neuroprotection and Treating Psychiatric Sequelae Stemming from Stress

Zhu

Liu

Gao

et al. 2023

Preprint

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The coronavirus disease 2019 (COVID-19) pandemic has affected the mental health of individuals worldwide, and the risk of psychiatric sequelae and consequent mental disorders has increased among the general population, health care workers and patients with COVID-19. Achieving effective and widespread prevention of pandemic-related psychiatric sequelae to protect the mental health of the global population is a serious challenge. Salidroside, as a natural agent, has substantial pharmacological activity and health effects, exerts obvious neuroprotective effects, and may be effective in preventing and treating psychiatric sequelae and mental disorders resulting from stress stemming from the COVID-19 pandemic. Herein, we systematically summarise, analyse and discuss the therapeutic effects of salidroside in the prevention and treatment of psychiatric sequelae as well as its roles in preventing the progression of mental disorders, and fully clarify the potential of salidroside as a widely applicable agent for preventing mental disorders caused by stress; the mechanisms underlying the potential protective effects of salidroside are involved in the regulation of the oxidative stress, neuroinflammation, neural regeneration and cell apoptosis in the brain, the network homeostasis of neurotransmission, HPA axis and cholinergic system, and the improvement of synaptic plasticity. Notably, this review innovatively proposes that salidroside is a potential agent for treating stress-induced health issues during the COVID-19 pandemic and provides scientific evidence and a theoretical basis for the use of natural products to combat the current mental health crisis.

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Section: Conclusion and Remarksmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Brain Network Homeostasis and Plasticity of Salidroside for Achieving Neuroprotection and Treating Psychiatric Sequelae Stemming from Stress

Zhu

Liu

Gao

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Telepsychiatry experienced an unexpected boost [16,17] and has been celebrated as a promising approach to mental health problems globally [18][19][20]. However, group activities had severe limitations transitioning to virtuality, individuals committed to inpatient units got increasingly isolated, people with no access to technology were segregated, and remote forms of care posed significant challenges for both workers and patients [21,22].…”

Section: Sars-cov-2 Pandemic and Mental Healthmentioning

confidence: 99%

“About Navigating Chaos”: Latin American and Caribbean Mental Health Workers’ Personal Impact Due to SARS-CoV-2 in the First Hundred Days

Agrest

Rosales

Fernández

et al. 2022

Int J Public Health

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Objectives: The personal impact of COVID-19 on mental health care workers (MHWs) has received scarce attention despite their work addressing the emotional wellbeing of those affected by the pandemic. This study aims to analyze Latin American and Caribbean’s MHWs’ subjective impact in connection to working during the initial times of the pandemic.Methods: One hundred and fifty-five persons (n = 155) from seventeen countries were contacted in May–June 2020 through a snowball approach. Complementary methodological strategies of analysis used for data triangulation included content analysis, thematic analysis, and interpretative phenomenological analysis.Results: Participants reported feelings of fear, anxiety, anguish, and fatigue. Milder negative impacts (e.g., uncertainty, concern), and complex feelings (e.g., ambivalence) were also frequent. One third of participants acknowledged their capacity to learn from this situation and/or experience satisfaction.Conclusion: Mental health of MHWs in Latin America and the Caribbean were under severe strain and the ongoing mental health reforms at risk during the pandemic’s beginning. More research and additional care may be needed to offer support to those involved in caring for the wellbeing of others.

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Effect of salidroside on neuroprotection and psychiatric sequelae during the COVID-19 pandemic: A review

Zhu,

Liu,

Gao

et al. 2024

Biomedicine & Pharmacotherapy

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COVID-19 and global mental health

Cited by 4 publications

References 1 publication

Brain Network Homeostasis and Plasticity of Salidroside for Achieving Neuroprotection and Treating Psychiatric Sequelae Stemming from Stress

Brain Network Homeostasis and Plasticity of Salidroside for Achieving Neuroprotection and Treating Psychiatric Sequelae Stemming from Stress

“About Navigating Chaos”: Latin American and Caribbean Mental Health Workers’ Personal Impact Due to SARS-CoV-2 in the First Hundred Days

Effect of salidroside on neuroprotection and psychiatric sequelae during the COVID-19 pandemic: A review

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