Effects of <i>Pediococcus pentosaceus</i> LI05 on immunity and metabolism in germ-free rats

Jiang, Shiman; Xia, Jiafeng; Lv, Longxian; Wang, Qiangqiang; Li, Yating; Xu, Qiaomai; Bian, Xiaoyuan; Ye, Jianzhong; Yang, Liya; Jiang, Huiyong; Ren, Yan; Wang, Kaicen; Fang, Daiqiong; Li, Lanjuan

doi:10.1039/d0fo02530e

Cited by 8 publications

(6 citation statements)

References 50 publications

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“…During the experiment, the levels of IL-6, IL-10, and TNF-α in the three groups were similar, indicating that the L. plantarum Y42 in biofilm and planktonic states did not cause an inflammatory response in the healthy Balb/c mice. A previous study showed that P. pentosaceus LI05 significantly reduced the serum proinflammatory cytokine levels, which is not in line with our results [32]. However, research showed that excessive amounts of proinflammatory cytokines could cause intestinal tissue injury and damage the body's immune balance [33].…”

Section: Effects Of Biofilm and Planktonic L Plantarum Y42 Administra...contrasting

confidence: 90%

Lactiplantibacillus plantarum Y42 in Biofilm and Planktonic States Improves Intestinal Barrier Integrity and Modulates Gut Microbiota of Balb/c Mice

Zhang

Yuan

et al. 2022

Foods

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In our previous study, Lactiplantibacillus plantarum Y42 showed some potential probiotic functions and the ability to form biofilm. The aim of this study was to compare the similarities and differences in the probiotic and physiological traits of L. plantarum Y42 in the biofilm and planktonic states. L. plantarum Y42 in the biofilm state was proven to have higher survival after passing through mimic gastrointestinal fluid, as well as excellent adhesion properties on the HT-29 cell monolayers, than those in the planktonic state. The expression of tight junction proteins (TJ proteins) of HT-29 cell monolayers treated by L. plantarum Y42 in the planktonic state increased, while similar changes were not observed in the HT-29 cells treated by the strain in the biofilm state. Furthermore, Balb/c mice were orally administered L. plantarum Y42 in the biofilm and planktonic states, respectively. Compared to the planktonic state, the oral administration of L. plantarum Y42 in the biofilm state significantly boosted IgA levels and improved the immunity of the mice. High-throughput sequencing showed that the diversity and structure of the intestinal flora of the mice were changed after the oral administration of L. plantarum Y42, including the up-regulated relative abundance of Lactobacillus in the intestinal tract of the mice, with no difference between the biofilm and planktonic states. Moreover, oral administration of L. plantarum Y42 in biofilm and planktonic states reduced the release of proinflammatory factors, to a certain extent, in the serum of the mice. The similarities and differences in the probiotic and physiological properties of L. plantarum Y42 in the biofilm and planktonic states can be contributed to the reasonable application of the strain.

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Section: Effects Of Biofilm and Planktonic L Plantarum Y42 Administra...contrasting

confidence: 90%

Lactiplantibacillus plantarum Y42 in Biofilm and Planktonic States Improves Intestinal Barrier Integrity and Modulates Gut Microbiota of Balb/c Mice

Zhang

Yuan

et al. 2022

Foods

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“…Intestinal microecological balance is well known to benefit multiple aspects of host physiology, including nutrition intake, 17 metabolism, 18 immune regulation, 19 and resistance to pathogens. 20 Therefore, the deprivation of intestinal microbiota makes a huge impact on the health and metabolism of host animal.…”

Section: Discussionmentioning

confidence: 99%

Alteration of gut microbiome and metabolome by Clostridium butyricum can repair the intestinal dysbiosis caused by antibiotics in mice

Liu¹,

Qiu²,

Yang³

et al. 2023

iScience

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“…64 Jiang et al found that germ-free rats gavaged with P. pentosaceus LI05 had increased intestinal subepidermal CD4+ cell levels. 65 Despite the attractiveness of probiotics such as L. plantarum as a tool to beneficially alter the intestinal microbiota, its immunological effects are still incompletely understood. Hence further detailed studies are needed to confirm this speculation.…”

Section: Discussionmentioning

confidence: 99%

Maternal supplementation with human milk-derived Lactiplantibacillus plantarum WLPL04 affects the immunity and gut microbiota of offspring rats

Zhong

Wang

et al. 2023

Food Funct.

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Effects of Pediococcus pentosaceus LI05 on immunity and metabolism in germ-free rats

Abstract: Many Pediococcus spp. have health-promoting benefits, and Pediococcus pentosaceus LI05 is one species that has been proven to be beneficial in previous studies. Our research aimed to determine the immune...

Cited by 8 publications

References 50 publications

Lactiplantibacillus plantarum Y42 in Biofilm and Planktonic States Improves Intestinal Barrier Integrity and Modulates Gut Microbiota of Balb/c Mice

Lactiplantibacillus plantarum Y42 in Biofilm and Planktonic States Improves Intestinal Barrier Integrity and Modulates Gut Microbiota of Balb/c Mice

Alteration of gut microbiome and metabolome by Clostridium butyricum can repair the intestinal dysbiosis caused by antibiotics in mice

Maternal supplementation with human milk-derived Lactiplantibacillus plantarum WLPL04 affects the immunity and gut microbiota of offspring rats

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