Ashwagandha: Advances in plant biotechnological approaches for propagation and production of bioactive compounds

Namdeo, Ajay G.; Ingawale, Deepa K.

doi:10.1016/j.jep.2020.113709

Cited by 14 publications

(7 citation statements)

References 115 publications

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“…Cell suspensions encompass a homogeneous cell population, which produces uniform and rapid nutrient and plant growth regulators. They also easily accommodate several biotechnological strategies such as elicitation, precursor feeding, and bioconversion or biotransformation, as well as mass production in bioreactors (scale-up) [ 7 ]. Several important plant-derived bioactive compounds have been produced using callogenesis and cell suspension technologies, whereby the majority were obtained using cell suspensions [ 98 ].…”

Section: Plant Tissue Culture Techniques For the Production Of Valuab...mentioning

confidence: 99%

“…They can easily be defined as biotechnological techniques that rely on the use of nutritive culture media and controlled aseptic conditions to ensure the culture and development of plant cells, tissues, and organs [ 6 ]. This technology shows many advantages over conventional agricultural practices such as (i) secondary metabolite production that occurs independent of the intrinsic or extrinsic factors that may affect crop growth and yield, (ii) the yield of desired phytochemical constituents by ensuring a constant production, and (iii) production under controlled conditions, thus limiting the risk of contamination by agrochemicals (pesticides, insecticides, herbicides, chemical fertilizers) [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Biotechnological Approaches to Producing Natural Antioxidants: Anti-Ageing and Skin Longevity Prospects

Bouzroud

Maaiden

Sobeh

et al. 2023

IJMS

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Plants are the main source of bioactive compounds that can be used for the formulation of cosmetic products. Plant extracts have numerous proven health benefits, among which are anti-ageing and skin-care properties. However, with the increased demand for plant-derived cosmetic products, there is a crucial prerequisite for establishing alternative approaches to conventional methods to ensure sufficient biomass for sustainable production. Plant tissue culture techniques, such as in vitro root cultures, micropropagation, or callogenesis, offer the possibility to produce considerable amounts of bioactive compounds independent of external factors that may influence their production. This production can also be significantly increased with the implementation of other biotechnological approaches such as elicitation, metabolic engineering, precursor and/or nutrient feeding, immobilization, and permeabilization. This work aimed to evaluate the potential of biotechnological tools for producing bioactive compounds, with a focus on bioactive compounds with anti-ageing properties, which can be used for the development of green-label cosmeceutical products. In addition, some examples demonstrating the use of plant tissue culture techniques to produce high-value bioactive ingredients for cosmeceutical applications are also addressed, showing the importance of these tools and approaches for the sustainable production of plant-derived cosmetic products.

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Section: Plant Tissue Culture Techniques For the Production Of Valuab...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Biotechnological Approaches to Producing Natural Antioxidants: Anti-Ageing and Skin Longevity Prospects

Bouzroud

Maaiden

Sobeh

et al. 2023

IJMS

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“…The following Table 1 depicts the presence of bioactive compounds in the most commonly utilized Spices and Herbs. [59] ; (Zhang et al, 2016) [94] ; (Ho et al, 2013) Turmeric Curcuminoids (curcumin, desmethoxycurcumin, bismethoxycurcumin) (Komonsing et al, 2021) [42] ; (Zhang et al, 2015) [94] ; (Mathew and Hsu, 2018) [52] ; (Yadav et al, 2013) [93] ; (Syed et al, 2015) [82] ; (Sahne et al, 2016) [72] Curry leaves Carbazole alkaloids (Ganesan et al, 2013) [22] ; (Khedkar, 2015) [41] ; (Ghasemzadeh et al, 2014) [23] Coriander Linalool (Begnami et al, 2016) [7] ; (Kansal et al, 2011) [36] ; (Lodi et al, 2012) [46] Clove Eugenol (Nagababu et al, 2010) [56] ; (Shukri et al, 2010) [77] ; (Devi et al, 2010) [16] Mint Rosmarinic acid, caffeic acid, ferulic acid Mimica-Dukic and Bozin, 2008 [54] , (Tahira et al, 2011) [83] ; (Lee, 2010) [44] ; (Brown et al, 2019) [10] Giloy Tinosporide, tinosporine, giloinsterol, giloin (Choudhary et al, 2013) [14] ; (Sharma et al, 2019) [73] ; (Murugesan et al, 2021) [55] Ashwagandha Withanolide A and Withaferin A (Namdeo and ingawale, 2021) [57] ; (Pandey et al, 2017) [60] ; (Thirugnanasambantham and Senthil, 2016) [85] ; (Shasmita et al, 2017) [75] ; (Singh et al, 2017)…”

Section: Spices and Herbs And Presence Of Bioactive Compoundsmentioning

confidence: 99%

Influence of spices and herbs incorporation on popular Indian dairy products: A review

Sharma¹,

Kumari²

2022

Pharma Innovation

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Spices and Herbs have created a lot of awareness in today's culture, leading people to turn to nature for safer herbal remedies due to their various well-proven therapeutic benefits and absence of adverse effects. Furthermore, herbs are also well-known for their capacity to serve as natural preservatives, antioxidants, and flavor enhancers. Spices and Herbs include not just herbaceous plants, but also the bark, roots, leaves, seeds, flowers, and fruit of trees, shrubs, and woody vines, and have been used for millennia as both food and medicine. Spices and Herbs have been used as an extract, juices, or in dried forms in various Indian dairy products which have resulted in the enhancement of flavor, appearance, quality and overall health benefits. This review paper summarizes the effects of numerous Spices and Herbs used in sandesh, lassi, paneer, ghee and Ice cream.

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“…Medicinal plants are considered as a resource for bioactive compounds that can be used for obtaining pharmacopeial or non-pharmacopeial drugs, contributing to the rising interest and demand for plant-derived phytochemicals [14][15][16]. Their main activities include antioxidant, anti-inflammatory, antiproliferative, anticancer, anti-neurodegenerative disorders, and chronic diseases, among other health properties [17].…”

Section: Bioactive Compounds In Plantsmentioning

confidence: 99%

Engineering Considerations to Produce Bioactive Compounds from Plant Cell Suspension Culture in Bioreactors

Motolinía-Alcántara

Castillo‐Araiza

Rodrı́guez-Monroy

et al. 2021

Plants

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The large-scale production of plant-derived secondary metabolites (PDSM) in bioreactors to meet the increasing demand for bioactive compounds for the treatment and prevention of degenerative diseases is nowadays considered an engineering challenge due to the large number of operational factors that need to be considered during their design and scale-up. The plant cell suspension culture (CSC) has presented numerous benefits over other technologies, such as the conventional whole-plant extraction, not only for avoiding the overexploitation of plant species, but also for achieving better yields and having excellent scaling-up attributes. The selection of the bioreactor configuration depends on intrinsic cell culture properties and engineering considerations related to the effect of operating conditions on thermodynamics, kinetics, and transport phenomena, which together are essential for accomplishing the large-scale production of PDSM. To this end, this review, firstly, provides a comprehensive appraisement of PDSM, essentially those with demonstrated importance and utilization in pharmaceutical industries. Then, special attention is given to PDSM obtained out of CSC. Finally, engineering aspects related to the bioreactor configuration for CSC stating the effect of the operating conditions on kinetics and transport phenomena and, hence, on the cell viability and production of PDSM are presented accordingly. The engineering analysis of the reviewed bioreactor configurations for CSC will pave the way for future research focused on their scaling up, to produce high value-added PDSM.

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Ashwagandha: Advances in plant biotechnological approaches for propagation and production of bioactive compounds

Cited by 14 publications

References 115 publications

Biotechnological Approaches to Producing Natural Antioxidants: Anti-Ageing and Skin Longevity Prospects

Biotechnological Approaches to Producing Natural Antioxidants: Anti-Ageing and Skin Longevity Prospects

Influence of spices and herbs incorporation on popular Indian dairy products: A review

Engineering Considerations to Produce Bioactive Compounds from Plant Cell Suspension Culture in Bioreactors

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