Midterm Recanalization after Arterial Embolization Using Hydrogel-Coated Coils versus Fibered Coils in an Animal Model

Fohlen, Audrey; Namur, Julien; Ghegediban, Homayra; Laurent, Alexandre; Wassef, Michel; Pelage, Jean-Pierre

doi:10.1016/j.jvir.2018.05.005

Cited by 7 publications

(7 citation statements)

References 18 publications

(40 reference statements)

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“…Given the near ubiquitous observation of at least some arteriographically evident recanalization in both groups at follow-up, this animal model may not be well suited to studying that question, although one may be able to infer the relative resistance to recanalization from histologic findings. Fohlen et al (17), using a sheep model with otherwise similar design, compared hydrogel-coated coils to fibered coils, some identical to those used in the present study, and found 33% recanalization in the coil group at 7 days, 50% at 1 month, and 75% at 4 months . This suggests that animal models in general may be more prone to recanalization than humans.…”

Section: Discussionmentioning

confidence: 51%

“…At follow-up, arteriograms of the treated arteries were performed. Arteriograms were graded for degree of occlusion using the scale of Fohlen et al (17): occlusion (Fig 3a), partial recanalization (Fig 3b), and complete recanalization (Fig 3c). Prior to euthanasia, systemic heparin (300 IU/kg intravenously) was administered to reduce postmortem thrombus formation.…”

Section: Follow-up Proceduresmentioning

confidence: 99%

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Nylon Fibered Versus Non-Fibered Embolization Coils: Comparison in a Swine Model

Trerotola

Pressler

Premanandan

2019

Journal of Vascular and Interventional Radiology

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Purpose: To determine whether nylon fibers improve the performance of platinum embolization coils in porcine arteries. Materials and Methods: Platinum 0.035" embolization coils, both with and without nylon fibers, were used to embolize a total of 24 hindlimb arteries in 6 swine: 12 with fibered coils and 12 with non-fibered coils. Apart from fibers, the coils were identical. Immediate and late results were studied, including number of coils needed to achieve vessel occlusion and durability of occlusion at 1 and 3 months. Arteriographic as well as histopathologic analysis were performed. Results: A mean of 3.2 (range, 2-4) non-fibered coils was required to achieve occlusion, whereas a mean of 1.3 (range, 1-2) fibered coils achieved occlusion in similarly sized arteries (2.3-3.2-mm diameter, P < .001). The mean percent cross-sectional area occupied by thrombus was greater in arteries with fibered coils than with non-fibered coils at 1 month (63% ± 6% and 48% ± 15%, respectively, P ¼ .03) but not at 3 months (61% ± 6% and 49% ± 15%, respectively, P ¼ .06). Some recanalization was observed at follow-up and did not differ between groups at 1 month (P ¼ .07) or 3 months (P ¼ .22). Conclusions: Nylon fibers allow significantly fewer embolization coils to achieve acute occlusion of arteries compared to bare metal coils. Both fibered and non-fibered coils showed recanalization at follow-up.

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Section: Discussionmentioning

confidence: 51%

Section: Follow-up Proceduresmentioning

confidence: 99%

Nylon Fibered Versus Non-Fibered Embolization Coils: Comparison in a Swine Model

Trerotola

Pressler

Premanandan

2019

Journal of Vascular and Interventional Radiology

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“…The authors do not specify whether the 39 patients with recanalization were the same 39 patients undergoing retreatment. Regardless, there is growing evidence that the mechanism of recanalization in coil embolization (the majority of PAVMs were treated with coils in this series) is thrombus breakdown and not neovascularity per se (9). Thus, whereas enhanced angiogenesis might cause pulmonary-to-pulmonary or systemic-to-pulmonary persistence, these constitute the minority of persistence causes.…”

mentioning

confidence: 78%

Persistence of Pulmonary Arteriovenous Malformation after Embolization: Another Reason to Quit Smoking

Trerotola

Pyeritz

2019

Radiology

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“…Additionally, hydrocoils have a lower midterm recanalisation rate compared with fibered coils. 10 The other major advantage is the detachment controller system, activated by the user allowing a precise placement with minimal movement. Without controlled deployment, complete vessel occlusion close to the origin of a feeding artery may be difficult to achieve, since the last coil may protrude into the feeding artery.…”

Section: Discussionmentioning

confidence: 99%

Benefit of vessel closure with the Azur CX Peripheral Coil System in small children with complex CHD

2020

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Vessel occlusion is a frequently used procedure to close congenital or acquired collaterals or communications. We report two cases of successful vessel closure, in small infants with CHD, using the Azur CX Peripheral Coil System. The low profile of the device, the controlled delivery of the coils, and the delivery through a microcatheter make it particularly interesting for the occlusion of highly tortuous vessels in children.

show abstract

Midterm Recanalization after Arterial Embolization Using Hydrogel-Coated Coils versus Fibered Coils in an Animal Model

Cited by 7 publications

References 18 publications

Nylon Fibered Versus Non-Fibered Embolization Coils: Comparison in a Swine Model

Nylon Fibered Versus Non-Fibered Embolization Coils: Comparison in a Swine Model

Persistence of Pulmonary Arteriovenous Malformation after Embolization: Another Reason to Quit Smoking

Benefit of vessel closure with the Azur CX Peripheral Coil System in small children with complex CHD

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