Introduction Animal bites are a significant public health problem, with the majority of bites coming from dogs, cats and humans. These may presented as punctures, abrasions, tears, or avulsions [1]. In general, animals bite occur as a natural, instinctive behavior, especially when they feel threatened or try to get food. An animal bite can cause infection in victims (in both humans and other animals) [2]. One of the most important diseases transmitted by animal bites is rabies. Rabies is one of the most dangerous viral zoonosis, and all mammals can develop the disease [3, 4]. The cause of the disease is a viral nerve-related friend which is belonged to the Rhabdo virus family from the type of Lyssa virus. The disease is mainly transmitted through biting and sometimes through mucous tissue, respiratory tract, placenta, contaminated equipment and transplant organs [5, 6]. Rabies is found in two types of epidemiologic condition: of the city type that is principally released by dogs or rarely by cat species, and the wild type whose repository is wolf, fox, raccoon, weasel and bat because of its fatality, an increasing number of animal bites in human, the loss of livestock and economic damage that can produce by rabies, it is very important. About 97% of deaths from rabies are due to dog bite [7]. Rabies is one of the diseases that has been neglected. this disease is preventable by vaccine, and most deaths occur due to the lack of awareness and poor access to health care [8]. Also, animal bites have serious medical consequences such as the risk of rabies, stroke, wound infection and medical expenses for the health system [9, 10]. More than 2.5 million people worldwide are exposed to prophylaxis after being exposed to animal bites [11]. In addition to the financial costs of preventing and treating