Effects of Tianmagouteng particles on brain cognitive function in spontaneously hypertensive rats with hyperactivity of liver-yang: A [F-18] FDG micro-PET imaging study

Metabolomics and 16S rRNA Gene Sequencing Analyses of Changes in the Intestinal Flora and Biomarkers Induced by Gastrodia-Uncaria Treatment in a Rat Model of Chronic Migraine

“…(GE and UR, [GU]) are the main herbs in the GU decoction, which has shown significant efficacy in vascular headache (Jiang, 2007). The prescription preparation, GU granules, in particular, are commonly used for treating neurological conditions such as migraine (Zhang et al, 2017). Extracts of GE and UR have been reported to exert neuroprotective effects (Xian et al, 2016;Liu et al, 2018); however, the oral absorption bioavailability of GE and UR extract is poor (Ge et al, 2014).…”

Tianma Gouteng decoction for essential hypertension

“…[ 12 ] A new animal study shows that TGD could alleviate cognitive dysfunction in rats with hypertension, which was possibly by inducing alteration of glucose metabolism in different brain regions with corresponding functions. [ 13 ]…”