“…The increasing demands of information technology for miniaturization and function density prompts the research community to develop intelligent materials which can serve as molecular logic gates to conduct molecular computing and provide measurable output [ [9], [10], [11], [12], [13], [14], [15]]. Enlightened by the pioneering work of de Silva in 1993 [16], all 16 fundamental logic gates, advanced circuits, and even neural network molecular logic gate, have been successfully demonstrated using various chemical systems including organic fluorophores, biomacromolecules and nanomaterials [ [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31] , [32], [33], [34], [35], [36]]. Although the promising performance of the reported materials, it is still compelling to investigate new intelligent materials for advanced molecular logic gates which show better operation stability and applicability for biomedical applications.…”