A homogeneous and “off–on” fluorescence aptamer-based assay for chloramphenicol using vesicle quantum dot-gold colloid composite probes

Miao, Yang‐Bao; Ren, Hong‐Xia; Gan, Ning; Zhou, You; Cao, Yuting; Li, Tianhua; Chen, Yinji

doi:10.1016/j.aca.2016.04.060

Cited by 43 publications

(21 citation statements)

References 34 publications

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“…water, h = honey, hs = human serum, hp = human plasma, hu = human urine, lw = lake water, m = milk, me = meat, mb = mouse blood, mu = mouse urine, ms = mouse serum, p = pork, rs = rat serum, rw = river water, sa = salvia, st = standard, tw = tap water, sw = spiked water, ww = waste water, uw = ultrapure water. [41,147]…”

Section: Discussionmentioning

confidence: 99%

“…Miao and colleges developed seven different aptasensing strategies for chloramphenicol detection [148-152, 40, 41]. Two aptasensors based on a colorimetric [148,149], one of them using an electrochemiluminescence [150] and four aptasensors based on fluorometric principle [40,151,41,152]. In each study the high specificity of the proposed sensor and possible cross-reactivities with interfering substances were demonstrated by measurements once in the presence of other antibiotics, such as kanamycin, tetracycline and oxytetracycline and further of a mixture containing chloramphenicol and various antibiotics.…”

Section: Chloramphenicolmentioning

confidence: 99%

“…Based on the mentioned aptasensor with DIL-encapsulating liposome as nanotracer, Miao et al [41] introduced a "off-on" fluorometric aptasensor, using vesicle QD-Au colloid composite probes. Here, the vesicle nanotracer as signal probe consisted of liposome-CdSe/ZnS QD complex labelled with SSB.…”

Section: Chloramphenicolmentioning

confidence: 99%

“…Quantum dots (QDs), semiconductor nanoparticles, belong to the UCNPs. Due to their influenceable optical and electronic properties, they are of interest for many applications and are applied as alternative to molecular fluorophores in optical biosensors [39][40][41]. QDs are very small particles, with good conductivity, a high extinction coefficient, high chemical stability, broadband optical absorption, low toxicity and strong photoluminescence emission [42,43].…”

Section: Introductionmentioning

confidence: 99%

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Aptamer-based Biosensors for Antibiotic Detection: A Review

Mehlhorn

Rahimi

Joseph

2018

Preprint

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Antibiotic resistance and accordingly their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develope robust, easy, and sensitive methods for rapid evaluation of antibiotic and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recent developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics like β-lactams, Aminoglycosides, Anthracyclines, Chloramphenicol, (Fluoro)Quinolones, Lincosamide, Tetracyclines and Sulfonamides are presented in this paper.

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Section: Discussionmentioning

confidence: 99%

Section: Chloramphenicolmentioning

confidence: 99%

Section: Chloramphenicolmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Aptamer-based Biosensors for Antibiotic Detection: A Review

Mehlhorn

Rahimi

Joseph

2018

Preprint

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“…QDs have been used directly or in conjugation with a biosensing element (i.e., aptamer) for the detection of pesticides and veterinary drug residues [117]. QDs have been used several times as quenchers in FRET-based aptasensors for the detection of antimicrobial residues in food products [83,86,87]. developed an aptasensor for the detection of streptomycin in milk [95].…”

Section: Figurementioning

confidence: 99%

The Growing Interest in Development of Innovative Optical Aptasensors for the Detection of Antimicrobial Residues in Food Products

Gaudin¹

2020

Biosensors

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The presence of antimicrobial residues in food-producing animals can lead to harmful effects on the consumer (e.g., allergies, antimicrobial resistance, toxicological effects) and cause issues in food transformation (i.e., cheese, yogurts production). Therefore, to control antimicrobial residues in food products of animal origin, screening methods are of utmost importance. Microbiological and immunological methods (e.g., ELISA, dipsticks) are conventional screening methods. Biosensors are an innovative solution for the development of more performant screening methods. Among the different kinds of biosensing elements (e.g., antibodies, aptamers, molecularly imprinted polymers (MIP), enzymes), aptamers for targeting antimicrobial residues are in continuous development since 2000. Therefore, this review has highlighted recent advances in the development of aptasensors, which present multiple advantages over immunosensors. Most of the aptasensors described in the literature for the detection of antimicrobial residues in animal-derived food products are either optical or electrochemical sensors. In this review, I have focused on optical aptasensors and showed how nanotechnologies (nanomaterials, micro/nanofluidics, and signal amplification techniques) largely contribute to the improvement of their performance (sensitivity, specificity, miniaturization, portability). Finally, I have explored different techniques to develop multiplex screening methods. Multiplex screening methods are necessary for the wide spectrum detection of antimicrobials authorized for animal treatment (i.e., having maximum residue limits).

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