Diagnosis and management of hair loss in children

Castelo‐Soccio, Leslie

doi:10.1097/mop.0000000000000376

Cited by 4 publications

(6 citation statements)

References 33 publications

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“…Sometimes, the definite diagnosis is difficult and active medical treatments are limited, though (non-cicatricial) alopecia is prevalent and causing hair loss. 2,3 Alopecia areata (AA) is one of the most frequent forms of human hair loss due to thumping T-cell response against hair follicle-autoantigen, non-scarring, the pattern of alopecia that presents in the areas circularly sharply defined. 4,5 Alopecia areata is divided according to the pattern plus severity of hair loss.…”

Section: Introductionmentioning

confidence: 99%

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Estimation of CD3, CD4, and CD8 in Iraqi patients with alopecia areata and alopecia universalis

Aldaffaie

Hussein

Muhieldden

2021

J of Cosmetic Dermatology

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Background Alopecia areata is considered to be an autoimmune disease characterized by T‐cell response and production of cytokines around the anagen stage. Aim of the study The aim of this study was to assess T cells in blood using immune biomarkers (CD3, CD4, and CD8) in patients with AA and AU compared with healthy individuals. Materials and methods This study was carried out at private clinic and in the Department of Dermatology in Al Karama Teaching Hospital. The study groups included 58 patients from different geographic areas in Iraq, with ages ranging from 5 to 48 years from the end of August 2019 to the January 2020; AA patient group included 19, AU patient group included, 11 and control group included 30 with no scalp or body lesions in their disease history. All patients were clinically diagnosed to detect clinical types of disease in the scalp, in the body, and any hair‐bearing area. Venous blood samples were collected from all participants where CD3 T cell, CD4 T cell, and CD8 T cell in whole blood were estimated by flow cytometry technique. Results The present study has found the males are more susceptible to infection than the females in both types of disease. There was no significant difference (p > 0.05) detected for immune biomarkers (CD3, CD4, and CD8) in blood between patient groups in comparison with healthy individuals, but there was a significant decrease (p ≤ 0.05) in immune biomarkers (CD8, CD3) according to stress status in AU and in CD8 T cell between patient groups. CD4/CD8 ratio increased in alopecia patients. Conclusion In current study, There was no significant difference detected for biomarkers (CD3, CD4, and CD8) in blood between patient groups and healthy control, but significantly decrease in CD8 T cell and CD3T cell according to stress in AU, and in CD8T cell between patient groups according to stress This research may have proven one of the theories. Study of CD markers receptors and B cell receptors these will help for future studies.

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Section: Introductionmentioning

confidence: 99%

“…However, the severity of hair loss can range from small and complete body area; alopecia is one of the most common challenges encountered in the practice of dermatology. Sometimes, the definite diagnosis is difficult and active medical treatments are limited, though (non‐cicatricial) alopecia is prevalent and causing hair loss 2,3 …”

Section: Introductionmentioning

confidence: 99%

Estimation of CD3, CD4, and CD8 in Iraqi patients with alopecia areata and alopecia universalis

Aldaffaie

Hussein

Muhieldden

2021

J of Cosmetic Dermatology

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“…4 Pemeriksaan penunjang diagnosis AA antara lain pemeriksaan hair pull test, dermoskopi/ trikoskopi, trikogram, dan histopatologi. 10,12,18 ,Hair pull test berupa tarikan bundel berjumlah 20 -60 rambut secara lembut dari pangkal rambut hingga ke distal menggunakan ibu jari dan telunjuk. Pemeriksaan ini dianggap positif apabila lebih dari 10% rambut tercabut.…”

Section: Diskusiunclassified

“…Pada AA, pemeriksaan ini positif walaupun bukan patognomonik. 10,18 Dermoskopi dapat menunjukkan gambaran karakteristik AA pada rambut berupa "exclamation mark", yellow dot, dan black dot. Trikogram akan menunjukkan gambaran tapered hair.…”

Section: Diskusiunclassified

Diagnosis Alopesia Areata Pada Anak: Kasus Serial

Toena

Danarti

2022

CDK

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<p>Alopesia areata (AA) merupakan penyakit autoimun yang ditandai dengan alopesia non-sikatrisial. Kondisi ini merupakan dermatosis yang umum ditemui pada anak. Gambaran klinisnya berupa alopesia non-sikatrisial fokal, perlu dibedakan dari kondisi dapatan serupa lainnya, terutama yang sering terjadi pada anak. Kami melaporkan 5 kasus AA pada anak berusia di bawah 18 tahun. Diagnosis berdasarkan pemeriksaan klinis dan penunjang. Pemahaman karakteristik AA perlu diketahui untuk diagnosis, terutama pada pasien anak.</p><p>Alopecia areata (AA) is a chronic autoimmune disease characterized by non-scarring alopecia. It is one of the most commonly found dermatosis in pediatric population. The clinical manifestations of focal non-scarring alopecia must be differentiated from other acquired focal non-scarring alopecia, especially those in children. This paper report 5 AA cases in children. Diagnosis was based on clinical and supporting examinations. Understanding the characteristics of AA, particularly in children, is important to make correct diagnosis.</p>

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“…ED has been reported to be applicable in diagnosing and assessing a wide range of diseases beyond melanomas and cutaneous malignancies [1][2][3]. Variants of ED have also been utilised to examine diseases of the hairs [6][7][8], nails [6,9,10], and capillaries [9]. The range of research involving ED is thus extremely wide.…”

Section: Researchmentioning

confidence: 99%

Roles of Epiluminescence Dermoscopy beyond the Diagnoses of Cutaneous Malignancies and Other Skin Diseases

Chuh

2017

IJTDH

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Epiluminescence dermoscopy was developed mainly for the diagnoses of melanoma and other skin cancers. This technology is also being increasingly applied for the diagnoses of other cutaneous diseases. With rising popularity and availability, dermoscopes are taking up other roles. We discussed how dermoscopes facilitate education and counselling for patients and parents of patients, modify health-related behaviour, clinical research, and dermoscope-guided operations and procedures.

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Diagnosis and management of hair loss in children

Cited by 4 publications

References 33 publications

Estimation of CD3, CD4, and CD8 in Iraqi patients with alopecia areata and alopecia universalis

Estimation of CD3, CD4, and CD8 in Iraqi patients with alopecia areata and alopecia universalis

Diagnosis Alopesia Areata Pada Anak: Kasus Serial

Roles of Epiluminescence Dermoscopy beyond the Diagnoses of Cutaneous Malignancies and Other Skin Diseases

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