Structural characterization of an intestinal immune system-modulating arabino-3,6-galactan-like polysaccharide from the above-ground part of Astragalus membranaceus (Bunge)

Characteristics and intestinal immunomodulating activities of water‐soluble pectic polysaccharides from Chenpi with different storage periods

“…Peyer's patches are part of the gut‐associated lymphoreticular tissues and play an essential role in the uptake of antigen and initiation of the intestinal immune response . Some exogenous substances, known as immunomodulators, can activate the plasmablasts and regulatory T lymphocytes that exist in the Peyer's patches, and enhance the defence system of body . Some natural immunomodulators are regarded as potential ingredients for body health.…”

Hypoglycemic effect of the polysaccharides from Astragalus membranaceus on type 2 diabetic mice based on the “gut microbiota–mucosal barrier”

“…Bunge, a perennial herb of the leguminous family, is often used as medicine with its roots. 12 As one of the oldest and most frequently used herbs in Asian traditional medicine, A. membranaceus possesses properties such as anti-inflammatory, antidiabetic, tonic, antioxidant, hepatoprotective, antineoplastic, [13][14][15][16][17] etc. In addition to its medicinal applications, A. membranaceus is also used in nutraceutical products, including herbal teas, soft drinks, soups, and trail mixes.…”

Extraction of a Novel Cold-Water-Soluble Polysaccharide from Astragalus membranaceus and Its Antitumor and Immunological Activities

“…Hepatocellular cancer is a major health problem in Asia with a high incidence and rate of mortality [ 10 ] and although modern cancer therapies have been greatly improved, it is still difficult to take effective action during the terminal stage of cancer. At present, more attention is being given to finding effective strategies for completely eliminating tumor cells, such as vaccinotherapy [ 11 ] and immunotherapy [ 12 ]. Although, the security of effective vaccination makes it worthy of consideration, it will be very difficult to make this approach effective for the treatment of cancers generally.…”