Micronutrient intake and the presence of the metabolic syndrome

Abstract

Background:Dietary micronutrients have been proposed to protect against oxidative damage and related clinical complications.Aims:We aimed to compare the micronutrient intake between individuals with and without metabolic syndrome (MS).Materials and Methods:This cross-sectional study included 3800 men and women who were aged between 35 and 65 years. The diagnosis of the MS was based on International Diabetes Federation criteria. Dietary intake of participants was assessed using a questionnaire for 24 h dietary recall. Student's t-test and Mann–Whitney U-tests were used for comparing the micronutrient intake of subjects with or without the MS and the odds ratio for the presence of the MS was calculated for each micronutrient by control for total energy intake adjusted by the residue method.Results:The mean age of MS subjects and the control group was 48.8 ± 7.9 years and 47.6 ± 7.6 years, respectively. Energy-adjusted intake of vitamin E (P < 0.05), B2 (P < 0.01), and B12 (P < 0.05) was higher in normal women compared with women with MS. Energy-adjusted intake of vitamin B1 was significantly higher in women with MS. After logistic regression analysis, no significant association between micronutrient intake and MS was shown.Conclusion:We found no significant association between micronutrient intake and MS.

Associations between Dietary Antioxidant Intake and Metabolic Syndrome

“…Ford et al [ 14 ] concluded that subjects with MS had a significantly lower level of dietary vitamin A intake, but the total carotenoid intake was similar in the two compared groups; Zulet et al also suggested that vitamin A intake was related to several anthropometrical and biochemical measurements that were linked to MS manifestations in healthy young adults, but they did not evaluate the association between pro-vitamin A intake and MS. [ 33 ] Our study also found no significant association between dietary vitamin E intake and MS, and this conclusion is consistent with several former studies [ 14 , 21 ]. Several other epidemiological studies did not find a significant association between dietary antioxidants intake and MS: Bian et al [ 11 ] demonstrated that there was no negative correlation between the dietary antioxidant vitamins group and MS, Motamed et al [ 13 ] and Li et al [ 12 ] also found no significant association between dietary antioxidant intake and MS. Additionally, a few studies have suggested that antioxidant supplementation had no beneficial effects on MS [ 34 , 35 ].…”

“…[ 7 – 10 ] A limited number of studies [ 11 – 14 ] have explored the relationship between dietary antioxidants intake and MS, but the conclusions have been inconsistent. Puchau et al [ 8 ] suggested that total dietary antioxidant capacity may be a potential early indicator in those at risk of developing MS. Bian et al [ 11 ], Li et al [ 12 ] and Motamed et al [ 13 ] all denied the existence of a significant relationship between dietary antioxidants intake and MS. However, the studies of Bian et al [ 11 ] and Li et al [ 12 ] had small sample size (258 and 550 subjects, respectively), while the results from Li et al were only adjusted for age and sex.…”

Inadequacies in the habitual nutrient intakes of patients with metabolic syndrome: a cross-sectional study

“…However, findings regarding the association between antioxidant intake and the development of MS remain inconsistent. Wei et al [13] and Motamed et al [49] did not observe a significant association between the intake of vitamins A and E and the development of MS.…”

Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA

“…Emerging evidence from animal models has indicated a fundamental interplay between micronutrients and metabolic physiology with implications for health and disease 1 , 2 . An impaired energetic metabolism is often accompanied by a shortage of cellular energy supply and vice versa.…”