2-Octyl Cyanoacrylate Tissue Adhesive and Muscle Attachment to Porous Anophthalmic Orbital Implants

Abstract

2-Octyl cyanoacrylate is well tolerated in the orbit, inducing minimal inflammation. It effectively attaches muscles to porous implants without hindering permanent integration or vascularization. The exposure rate for unwrapped hydroxyapatite spheres was not caused by the adhesive, as evidenced by the lack of exposures in the porous polyethylene implant group. 2-Octyl cyanoacrylate may be effective in reducing the cost and time for enucleation surgeries when porous motility implants are used.

Preliminary in vitro Evaluation of 2-Octyl Cyanoacrylate (Dermabond??) to Seal Corneal Incisions

“…It has been suggested for wound closure in scleral buckling, 6 conjunctival wounds, 7 and orbital implants. 8 Complications associated with bioadhesive use in ocular tissues include infections, elevated intraocular pressure, cataract induction, and papillary conjunctivitis. The ability to close wounds with a thin surface film may alleviate some of these problems.…”

Tissue adhesives in ocular surgery

“…Octyl-2-cyanoacrylate tissue adhesive has been used for the attachment of muscles to porous orbital implants and the tensile strength of the glued fixation was found to be similar to sutured attachments [37]. Octyl-2 cyanoacrylate was found to have greater adhesive and tensile strength than conventional cyanoacrylate glue when tested in muscle reattachment surgery in patients having thin sclera.…”

Sutureless Ophthalmic Surgery: A Scaffold-Enhanced Bioadhesive Technique

“…Fibrin glue provided insufficient tensile strength, whereas cyanoacrylates produce stronger adhesions. [11][12][13][14] Although these bioadhesives can eliminate the complications associated with suturing ocular tissues, precise application of these liquid adhesives to the tissue site is difficult.…”