Quality of life of adolescents with type 1 diabetes

Costa, Luce Marina Freires Correa da; Vieira, Sandra Elisabete

doi:10.6061/clinics/2015(03)04

Cited by 28 publications

(36 citation statements)

References 16 publications

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“…When comparing the QOL of children and their parents with a chronic disease, it was revealed that the scores of QOL by parents are estimated lower on all scales of the questionnaire, except for social functioning (10). Adolescents are more resistant to accepting the disease than younger children because they no longer depend on their parents or guardians for care and are responsible for their own health (11,12).…”

Section: Discussionmentioning

confidence: 99%

Health-Related Quality of Life in Children with Type 1 Diabetes in Armenia

Markosyan

Perikhanyan²

2019

Iran J Pediatr

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Background: Type 1 diabetes mellitus (T1DM) is the life-threatening chronic disease if left without appropriate clinical care and self-management. Diabetes places a burden on family life and daily routine that can be reduced by a proper disease management program. Extensive research studies are conducted for the estimation of pediatric quality of life (PedsQL) in the medical and psychosocial care of diabetic children. Objectives: To evaluate the quality of life of children 8-12 y/o with T1DM, to compare PedsQL perceived by their parents, to understand influence of gender and other factors on PedsQL and disease management. Methods: Children with T1DM were identified and recruited from the pediatric endocrinology department registries. We used the validated adapted pediatric quality of life inventory 3.0 diabetes module of the child (ages 8-12) and parent reports. Obtained scales were compared between children and parents as well as between the two genders. Results: A total of 132 T1DM children and their primary caregivers participated in the study. The mean age of the children was 6.82 ± 2.17 years. Girls had higher (17.82 ± 1.59) body mass index (BMI) than boys (17.1 ± 1.95; OR = 0.72; P value 0.021). Mean levels of HbA1C were different in genders: 9 ± 1.78 for girls and 7.93 ± 1.0 for boys (P < 0.001). Diet habits of diabetic children with uneducated primary caregiver have not been changed (P value 0.0138) and these children more often experienced hypoglycemia (P < 0.001). Regular exercising had positive effect on level of HbA1C (7.8 ± 0.82 versus 8.93 ± 1.73) (P value 0.003). In a comparison of PedsQL scores between boys and girls, we have found significant differences in 17 items and in 15 items between child and parent. Conclusions: In 8-12 y/o group of T1DM children, girls seem to be more sensitive towards pain and difficulties associated with the disease, boys experienced more difficulties related to treatment compliance and parents' involvement. Primary caregivers mostly underestimated the child's PedsQL.

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Section: Discussionmentioning

confidence: 99%

Health-Related Quality of Life in Children with Type 1 Diabetes in Armenia

Markosyan

Perikhanyan²

2019

Iran J Pediatr

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“…The participants wanted young people to know that it was OK to be angry and upset, but that they could do what they wanted to do with few limitations. Although quality of life is a frequent focus of type 1 diabetes research ( 32 – 34 ), no studies have addressed the importance of children and adolescents with type 1 diabetes learning that they can still do the things they had previously planned on doing in life. Participants emphasized how important it is for parents and HCPs to demonstrate a positive attitude about type 1 diabetes and avoid comments that may validate young people’s belief that the life they knew is over because of their diagnosis.…”

Section: Discussion and Clinical Implicationsmentioning

confidence: 99%

Lessons Learned From a Life With Type 1 Diabetes: Adult Perspectives

2017

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Adults who have lived much of their life with type 1 diabetes have learned lessons that can benefit health care providers (HCPs), families, and young people who live with the condition. This study was undertaken to gain a better understanding of the challenges of growing up and living with type 1 diabetes from adults who have experienced those challenges and to recommend strategies for parents, caregivers, and HCPs who work with children or adolescents with type 1 diabetes. Thirty-five adults with type 1 diabetes participated in this qualitative study consisting of two in-depth interviews with each participant. Six themes emerged: 1) It’s not who you are. 2) Don’t let it limit you. 3) Get involved in diabetes support groups. 4) It’s going to be OK. 5) Teach them; don’t scare them. 6) Don’t single kids out. Through hindsight and the more mature perspective of adulthood, study participants were able to share valuable insights that could inform the efforts of those who work with or care for younger people with type 1 diabetes.

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“…It is a genetic-based autoimmune condition resulting from absolute insulin deficiency due to immune-mediated destruction of pancreatic β cells [1]. …”

Section: Introductionmentioning

confidence: 99%

Serum adipokines and vitamin D levels in patients with type 1 diabetes mellitus

Ismail¹,

Hamid²,

Ibrahim³

et al. 2017

aoms

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IntroductionAdiponectin, leptin and resistin are adipokines that play important roles in the regulation of lipid and carbohydrate metabolism in type 2 diabetes (T2DM). However, their influence in type 1 diabetes mellitus is still unknown. The aim of this study was to measure serum adiponectin, leptin and resistin levels and to investigate their relationships with vitamin D and other clinical and laboratory parameters in patients with type 1 diabetes.Material and methodsFifty subjects with type 1 diabetes and 50 healthy age- and sex-matched subjects were selected from the Endocrinology Outpatient Clinic of Cairo University Pediatrics Hospital. Enzyme-linked immunosorbent assay was used to measure the levels of leptin, adiponectin and resistin. Vitamin D levels were measured using electro-chemiluminescence immunoassay.ResultsThere were no significant differences in adiponectin and leptin levels between diabetic and control subjects (p = 0.6 and p = 0.5 respectively). Resistin levels were significantly higher in the diabetic group compared to controls (p < 0.001) and in postpubertal patients compared to prepubertal patients (p < 0.04). Serum resistin in type 1 diabetes showed a negative correlation with vitamin D (p < 0.001) and a positive correlation with glycated hemoglobin (HbA1c) (p = 0.006), while other adipokines were not interrelated.ConclusionsThese results strongly support a role of resistin and vitamin D deficiency in the pathophysiology of type 1 diabetes. Vitamin D may be involved in resistin regulation through an unknown mechanism. Further studies are recommended to understand resistin regulation in type 1 diabetes.

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Quality of life of adolescents with type 1 diabetes

Cited by 28 publications

References 16 publications

Health-Related Quality of Life in Children with Type 1 Diabetes in Armenia

Health-Related Quality of Life in Children with Type 1 Diabetes in Armenia

Lessons Learned From a Life With Type 1 Diabetes: Adult Perspectives

Serum adipokines and vitamin D levels in patients with type 1 diabetes mellitus

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