Adhesion to the monitoring of newborns from VDRL positive mothers

Abstract

OBJECTIVE:Treponema pallidum is the etiological agent of congenital syphilis, which results from fetal contamination by the infected mothers, who were not treated or were inadequately treated during pregnancy. METHODS: An observational, prospective and longitudinal study, was performed (2010)(2011)(2012)(2013)(2014), through the evaluation of 428 newborns during 18 months in a syphilis clinic from a Philanthropic Maternity Hospital in Aracaju, capital city of the Northeastern state of Sergipe, Brazil. The findings were statistically expressed as descriptive data and the statistical program used was SPSS (Statistical Package for Social Sciences). RESULTS AND CONCLUSIONS:The prevalence of congenital syphilis was 10.02/1,000 live births. A total of 120 (28%) of newborns did not attend the first appointment. During the observational period, at 18 months, the rate of abandonment was 75%. The average interval of healing of the newborns was 4.25 months. A high prevalence of congenital syphilis was found with low adhesion to the first consultation and monitoring period; 67.1% of newborns were treated with Crystalline Penicillin (Penicillin G) and only 3% of them required a repeat treatment.

Sífilis congênita e seu impacto na saúde dos recém-nascidos

“…Nesse sentido, Lopes et al, (2016), em seu estudo na mesma maternidade filantrópica em 2010 a 2014, evidenciou que 43,3% dos recém-nascidos de mães VDRL positivas, eram peso adequado para idade e 56,7% eram baixo peso ao nascer. Verificou-se também que 49,7% dos avaliados eram do sexo masculino.…”

Epidemiologia da Sífilis Congênita no estado de Sergipe

“…Em estudo prospectivo, observacional acerca da adesão e acompanhamento de recém-nascidos de mães com sorologia positivo para o Treponema pallidum, realizado na Maternidade Filantrópica de Aracaju, entre 2010 e 2014, evidenciou uma incidência média entre os anos estudados de 10,2 casos para cada mil nascidos vivos, 28% dos recém-nascidos não compareceram à primeira consulta para de tratamento da doença, a taxa de abandono do tratamento foi de 75%, o intervalo médio de cura desses recém-nascidos foi de 2,25 meses, dessa forma, a alta incidência da sífilis foi associadas à baixa adesão ao tratamento, apenas 67,1% dos recém-nascidos foram tratados com Penicilina Cristalina (Lopes et al, 2016).…”

Spatial analysis, temporal trend, and local risk of congenital syphilis new cases in Sergipe, Brazil

“…Additionally, 28% of the newborns did not attend the first consultation for treatment of the disease, the treatment abandonment rate was 75%, and the mean cure rate of these newborns was 2.25 months. The high incidence of syphilis was associated with low adherence to treatment, as only 67.1% of newborns were treated with crystalline penicillin [21]. In countries such as China, it has been recommended to use two doses of benzathine penicillin in the first and third quarters, respectively.…”