Extensive bulbar conjunctival Kaposi’s sarcoma as initial symptom of human
            immunodeficiency virus

Rossetto, Julia D.; Molles, Sandra; Gracitelli, Carolina P. B.

doi:10.5935/0004-2749.20190083

Cited by 6 publications

(3 citation statements)

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“…Although ocular presentations are noted in 20% of patients with AIDS [3], the bulbar conjunctiva is considered an unusual initial site for KS [12]. There have been only a few reported cases of conjunctival KS as the first presenting sign that led to the diagnosis of HIV in previously healthy individuals [4][5][6][7][8][9][10][11].…”

Section: Case Reports In Ophthalmologymentioning

confidence: 99%

“…In ocular tissues, KS may manifest in several areas, such as the orbit, lacrimal gland or sac, eyelids, caruncle, and bulbar or palpebral conjunctiva [3]. However, ocular KS as an initial presentation of acquired immunodeficiency syndrome (AIDS) or HIV infection is extremely rare and has been documented in only a few cases [4][5][6][7][8][9][10][11]. Furthermore, the conjunctiva is considered an uncommon site for the initial presentation of this tumor in patients with HIV/AIDS [12].…”

Section: Introductionmentioning

confidence: 99%

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Isolated Kaposi’s Sarcoma of the Bulbar Conjunctiva as an Initial Manifestation of AIDS: A Case Report

Alsawadi,

Al-Somali,

Najmi

et al. 2023

Case Rep Ophthalmol

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Kaposi’s sarcoma (KS) is a malignant vascular endothelium-cell-derived tumor caused by human herpesvirus 8. It is one of the most common tumors among human immunodeficiency virus (HIV)-infected patients; however, isolated KS is rarely reported as the initial presentation. This study describes a rare case in which isolated KS of the bulbar conjunctiva was the first presenting symptom leading to the diagnosis of HIV/acquired immunodeficiency syndrome (AIDS) in a 39-year-old man. The patient, who had no prior medical history, presented to the ophthalmology clinic with an isolated large, dark-reddish mass in the left bulbar conjunctiva and subconjunctival hemorrhage. The mass was first identified 6 months prior and had continued to grow since then. KS was confirmed based on the analysis of the incisional biopsy sample, subsequently prompting an HIV test, which was positive. This report highlights the recognition of KS as a relevant ocular complication and potential initial manifestation of AIDS. Additionally, KS should be considered in the differential diagnosis of any vascular lesion, even when present at uncommon sites.

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Section: Case Reports In Ophthalmologymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Isolated Kaposi’s Sarcoma of the Bulbar Conjunctiva as an Initial Manifestation of AIDS: A Case Report

Alsawadi,

Al-Somali,

Najmi

et al. 2023

Case Rep Ophthalmol

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“…Moreover, lesion growth depends on various cytokines and growth factors, including the Tat gene from the HIV genome. 9 We present the case of a 27-year-old male patient with newly diagnosed HIV infection and disseminated Kaposi sarcoma involving the skin, esophagus, stomach and probably, bulbar conjunctiva.…”

Section: Introductionmentioning

confidence: 99%

AIDS-related disseminated Kaposi Sarcoma: a case report

Ruiz

Díaz-Vintimilla

Trevilla-Viveros

et al. 2022

psrua

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Kaposi sarcoma (KS) is the most common malignant tumor in HIV-infected individuals. Although its most common form consists of skin and mucosal lesions, it can also present itself in a disseminated way affecting the gastrointestinal tract, lungs and eye structures. We present the case of a 27-year-old male patient with HIV infection and disseminated Kaposi sarcoma. Disseminated KS is an uncommon form of the disease. Therefore, it is important to take this into account, particularly in HIV-infected individuals with characteristic cutaneous lesions.

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Spotlight on ocular Kaposi’s sarcoma: an update on the presentation, diagnosis, and management options

Venkateswaran

Ramos

Cohen

et al. 2021

Expert Review of Ophthalmology

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Extensive bulbar conjunctival Kaposi’s sarcoma as initial symptom of human immunodeficiency virus

Cited by 6 publications

References 0 publications

Isolated Kaposi’s Sarcoma of the Bulbar Conjunctiva as an Initial Manifestation of AIDS: A Case Report

Isolated Kaposi’s Sarcoma of the Bulbar Conjunctiva as an Initial Manifestation of AIDS: A Case Report

AIDS-related disseminated Kaposi Sarcoma: a case report

Spotlight on ocular Kaposi’s sarcoma: an update on the presentation, diagnosis, and management options

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