Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Abstract

Approved by the following research ethics committee: Süleyman Demirel University (# 72867572-050). ABSTRACT Purpose:To evaluate anterior segment parameters in patients with pseudoexfoliation syndrome (PXS) using Scheimpflug imaging. Methods: Forty-three PXS patients and 43 healthy control subjects were included in this cross-sectional study. All participants underwent a detailed ophthalmologic examination. Anterior segment parameters were measured using a Scheimpflug system. Results: Considering the PXS and control groups, the mean corneal thicknesses at the apex point (536 ± 31 and 560 ± 31 µm, respectively, p=0.001), at the center of the pupil (534 ± 31 and 558 ± 33 µm, respectively, p=0.001), and at the thinnest point (528 ± 30 and 546 ± 27 µm, respectively, p=0.005) were significantly thinner in PXS patients. Visual acuity was significantly lower (0.52 ± 0.37 versus 0.88 ± 0.23, p<0.001) and axial length was significantly longer (23.9 ± 0.70 mm versus 23.2 ± 0.90 mm, p=0.001) in the PXS eyes than in the control eyes. There were no statistically significant differences in the mean values of keratometry, anterior chamber angle, anterior chamber depth, corneal volume, and anterior chamber volume between the PXS and control eyes. Conclusions: The patients with PXS had thinner corneas, worse visual acuity, and longer axial length compared with those in the healthy controls.

Preoperative and postoperative anterior segment parameters of cataract patients with pseudoexfoliation evaluated using the Sirius–Scheimpflug system and a comparison with healthy subjects

“…There is insu cient data in the literature regarding the effect of phacoemulsi cation surgery on ACD in patients with PEX. In the anterior chamber evaluation of patients with PEX by Güneş et al using a Scheimp ug camera, no signi cant difference was found in terms of ACD in patients with pseudoexfoliation [39]. In our study, in accordance with the literature, no signi cant difference was found between the pseudoexfoliation and non-pseudoexfoliation groups when all preoperative and postoperative ACD measurements were compared.…”

“…Studies on ACV in patients with cataract are discussed in the literature. Güneş et al found no signi cant difference between the pseudoexfoliation and the control groups in terms of ACV [39]. Doğanay et al found a signi cant increase in ACV after uneventful phacoemulsi cation using Pentacam [40].…”

Frequency and risk factors of narrow angles in patients with pseudoexfoliation: a case–control study

“…Secondly, several studies have suggested that certain ocular biometric characteristics (e.g. corneal thickness, AL, and ACD) in PXF patients may differ compared to healthy individuals [13,14], thus, such difference may anatomically predispose to narrow angles. Finally, as it is well known from previous studies that the incidence of PXF increases with age [15] and that the anterior chamber angle is narrower in older individuals [16], it is possible that the high rate of PXF is attributed to the older age of affected patients.…”

Evaluation of Anterior Segment Parameters in Pseudoexfoliative Glaucoma, Primary Angle-Closure Glaucoma, and Healthy Eyes

“…Several studies have measured ACA and other anterior segment parameters in healthy and glaucomatous eyes using different methods. 12 , 14 , 15 , 16 , 17 , 18 …”

“…They also reported that there were no significant differences in ACV, ACA, or CCT parameters among patients with pseudoexfoliation syndrome, those with PEXG, and healthy controls. 12 Guneş et al 15 evaluated anterior segment parameters in patients with pseudoexfoliation syndrome using dual Scheimpflug imaging and reported that there were no significant differences in ACA, ACD, or ACV values. Similarly, there were no statistically significant differences in ACA, ACD, or ACV between the patients with PEXG and the control group in our study.…”