Measurement of choroid thickness in pregnant women using enhanced depth imaging optical coherence tomography

Gonul, Saban; Ozturk, Banu Turgurt; Okudan, Süleyman

doi:10.5935/0004-2749.20150017

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…There are more than a dozen studies on choroidal thickness changes in pregnancy using enhanced depth imaging OCT, which have provided inconsistent results. [27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42] Some studies have found thickening of the choroid in specific subfields during the second and third trimester of pregnancy, whereas other studies have observed no difference in choroidal thickness during pregnancy. The discrepancy in these studies could be due to variation in inclusion criteria, confounding factors (i.e.…”

Section: Discussionmentioning

confidence: 99%

Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiography

Chanwimol

Balasubramanian

Nassisi

et al. 2019

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. To evaluate retinal vascular status during pregnancy by using optical coherence tomography angiography (OCTA). METHODS. Women in their third trimester of pregnancy and nonpregnant age-matched women were recruited for this prospective, case-control study. Subjects were imaged with OCTA. Main outcome measures were foveal avascular zone parameters, perfusion density (PD) percentage in the superficial retinal capillary plexus (SCP), PD percentage in the deep retinal capillary plexus (DCP), SCP vessel length density (VLD), DCP-VLD, and choriocapillaris (CC) flow voids (i.e., flow deficits in the CC). RESULTS. Nineteen eyes of 10 pregnant subjects and 44 eyes of 27 nonpregnant control women were included. Mean ages were 36 6 7 and 35 6 8 years (SD), respectively (P value ¼ 0.78). Mean gestational age of pregnant women was 33 weeks (range ¼ 29-39, SD ¼ 3). There was a significant reduction in the SCP-PD in the entire scan and in the nasal Early Treatment Diabetic Retinopathy Study subfield (47.9 vs. 49.7, P ¼ 0.04 and 49.3 vs. 51.6, P ¼ 0.03, respectively) in the pregnant cohort versus controls. There was a significant increase in the DCP-PD in the parafoveal region and in the temporal and inferior Early Treatment Diabetic Retinopathy Study subfields (58.0 vs. 55.9, P ¼ 0.03; 57.9 vs. 55.5, P ¼ 0.02; 58.0 vs. 55.9, P ¼ 0.05, respectively) in the pregnant cohort. There was no significant difference in foveal avascular zone parameters, SCP-VLD, DCP-VLD, or CC flow voids between the two populations. CONCLUSIONS. This study detected retinal vasculature changes in the third trimester of pregnancy. Mean SCP-PD was significantly decreased and mean DCP-PD was significantly increased without a difference in VLD.

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Section: Discussionmentioning

confidence: 99%

Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiography

Chanwimol

Balasubramanian

Nassisi

et al. 2019

Invest. Ophthalmol. Vis. Sci.

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“…However, taking OCT measurements at one selected point and comparing them with each other is not the most precise method for determining CTs, since these measurements, which are performed manually, may be affected by local irregularities of the choroid-scleral boundary. 17,21,22 Therefore, to reduce the risk of mistakes caused by this, we used three horizontal sections for the CT measurements, which were evaluated on these sections at three points, and used the average of these three measurements for comparisons. Also, the development of automatic software for CT measurements will, in the future, help to improve the accuracy of these measurements.…”

Section: Discussionmentioning

confidence: 99%

“…Also, the development of automatic software for CT measurements will, in the future, help to improve the accuracy of these measurements. 21,22 In addition, CT measurements may be affected by several factors such as age, gender, spherical equivalent, diurnal variation, smoking, coffee addiction, and some conditions such as diabetes mellitus and age-related macular degeneration. 18,21,[23][24][25][26] To eliminate these potentially confusing factors, the authors have statistically adjusted some of them for comparisons; however, these have not included all the factors mentioned above.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Choroidal Thickness in Non-arteritic Anterior Ischaemic Optic Neuropathy at the Acute and Chronic Stages

Gonul

Gedik

Köktekir

et al. 2016

Neuro-Ophthalmology

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The objective of this study was to evaluate the measurements of choroidal thickness (CT) in patients with non-arteritic anterior ischaemic optic neuropathy (NAION) at the acute and chronic stages. This case-control study compares three groups: Group 1 included 23 eyes of 23 patients with chronic NAION, Group 2 consisted of 24 eyes of 24 patients with acute NAION, and Group 3 included 24 eyes of 24 age-matched control subjects. The average CTs for Group 1, Group 2, and Group 3 were 261.24 ± 50.04, 280.05 ± 74.94, and 254.74 ± 50.11 µm, respectively. For all measurements, no statistical significance was found between the groups (p = 0.319, 0.357, 0.680, and 0.178 for the CTs as average, foveal, superior, and inferior, respectively). Similarly, there was no difference between the CT measurements of the affected and unaffected eyes in Group 1 and Group 2 (p = 0.571, 0.741 for average, respectively). The amount of time after the onset of the disease ranged from 6.0 to 48 months (23.86 ± 16.70 months) in Group 1 and from 1 to 30 days (7.45 ± 8.86 days) in Group 2. There was no correlation between the CTs and follow-up times in Group 1 (p = 0.768 for average) and no association between the CTs and the thicknesses of the retinal nerve fibre layers in Group 2 (p = 0.453 for average). CT is not directly influenced by NAION at either the acute or the chronic stage of the disease. These results may also demonstrate that the changes of CT do not increase the risk of experiencing a NAION attack. ARTICLE HISTORY

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Choroidal Thickness in Nonarteritic Anterior İschemic Optic Neuropathy

Gonul¹,

Okudan²

2015

American Journal of Ophthalmology

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Measurement of choroid thickness in pregnant women using enhanced depth imaging optical coherence tomography

Cited by 3 publications

References 5 publications

Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiography

Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiography

Evaluation of Choroidal Thickness in Non-arteritic Anterior Ischaemic Optic Neuropathy at the Acute and Chronic Stages

Choroidal Thickness in Nonarteritic Anterior İschemic Optic Neuropathy

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