Synthesis and X-ray crystallography of N,N'-di(2-hydroxybenzylidene)hydrazine

Abstract

The biologically active N,N '-di(2-hydroxybenzylidene)hydrazine has been synthesized and specifically characterized by X-ray crystallography. There are two molecules of N,N'-di(2-hydroxybenzylidene)hydrazine, C14H12N2O2, in the unit cell. The N,N'-di(2-hydroxy benzylidene)hydrazine molecule is planar, with maximum deviation from the mean plane being less than 0.028(2) Å. Intramolecular O-H···N hydrogen bonding interactions were observed in the crystal lattice which connected the molecules into chain running along baxis. KEYWORDS

N,N-Disubstituted-N′-acylthioureas as modular ligands for deposition of transition metal sulfides

“…There are a few reports of their use in AACVD but these studies do not explore the effects on decomposition temperature from varying the substituents on the ligand. 30, 31 Herein, we investigate the impact of the N-substituents, R and R′ on decomposition temperatures of Ni complexes and demonstrate that these ligands can be used for deposition of metal sulfides via AACVD.…”

Synthesis, crystal structure, and antidiabetic property of hydrazine functionalized Schiff base: 1,2-Di(benzylidene)hydrazine

“…The role of supramolecular interactions is also assessed for the construction of a long-range architecture. It is revealed that the Schiff base functionalized with hydrazine develops a one-dimensional supramolecular framework through long-distant C-H•••π interactions [42] (Figure 2, Table 3). In the formation of the long-range supramolecular architecture, the azomethine-N of the synthetic Schiff base involves very little interaction in the intermolecular hydrogen bonding as it is intramolecularly locked with imineproton while the phenyl-H contributes to a great extent through C-H•••π interactions.…”

Simple, novel, and efficient synthesis of ethyl 2-(2-(1H-indol-3-yl)benzo[d]thiazol-3(2H)-yl)-2-cyanoacetate or acetate via a three-component reaction

“…3 The sulfur-and nitrogen-containing aromatic heterocyclic compounds known as benzothiazoles and analogs play a crucial role in the synthesis of new drugs. 4 These compounds have different pharmacological and biological effects, and have different applications in the production of carbonic anhydrase enzyme inhibitory, 5,6 antiinflammatory, 7 anticancer, 7 antimicrobial, 8 antitumor, 8 Alzheimer, 9 antibacterial, 10 antiallergic, 11 and antioxidant 12 drugs. Benzothiazoles are also widely used in a variety of consumer and industrial products such as nonlinear optics (NLOs), textiles, α-glucosidase inhibitors, organic light-emitting diodes (OLEDs), fluorescent probes, and chemosensors.…”