Caracterização da tuberculose drogarresistente no Brasil, 2014*

Jacobs, Marina Gasino; Pinto, Vítor Laerte

doi:10.5123/s1679-49742019000300014

Cited by 7 publications

(4 citation statements)

References 18 publications

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“…The strategy aimed at reaching 90% case detection and treatment success by 2025 [5]. According to the 2020 globally milestones of the 'End TB Strategy', the annual reduction of TB prevalence should be by a rate of 4-5% [6,7]. However, Ethiopia is still one among the 30 high burdens TB countries and The TB case detection rate is very low compared to the World Health Organization (WHO) target of detecting all infectious TB cases [8].…”

Section: Introductionmentioning

confidence: 99%

Treatment seeking delay and associated factors among tuberculosis patients attending health facility in Ethiopia from 2000 to 2020: A systematic review and meta analysis

et al. 2021

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Background Treatment seeking delay is defined as the time interval between the onset of the major symptoms of tuberculosis (TB) and the first visit to the formal health care facility. The patient was said to be delayed if the patient visited the health-facility after 3 weeks onset of major symptoms. However, in low-income countries like Ethiopia, the delay in treatment-seeking among tuberculosis patients contributes to a widespread transmission and high prevalence of tuberculosis. Methods Studies were retrieved from PubMed, Cochrane Database, Cinahl, Scopus, Mednar, and Google Scholar by employing a combination of search terms with Boolean operators. Heterogeneity across studies was assessed using the Cochrane Q test. A funnel plot was used for visual assessment of publication bias. Subgroup analyses were performed to explore the possible causes of heterogeneity. Egger’s weighted regression test at a p-value < 0.05 was used to assess the presence of publication bias. Sensitivity analysis was performed to judge whether the pooled effect size was influenced by individual study. STATA software version 14 was used for all statistical analyses. Result A total of 12 studies with 5122 total sample size were included. The national pooled prevalence of treatment seeking delay was 44.29% (95% CI: 39.805, 48.771). The visual inspection of the funnel plot showed the asymmetrical distribution, and the Egger test showed insignificant (P = 0.348). Patients who did not seek formal health care providers on a first contact had about 7 times more likely to delay than patients who sought formal health care provider on a first contact (OR: 7.192 ((95% CI 5.587–9.257), P = 0.001, I2: 85%). The others independent predictors of delay were rural residence (OR: 3.459 ((95% CI 1.469–8.148), P ≤ 0.001), extra pulmonary TB (OR: 2.520 ((95% CI 1.761–3.605), 0.180), lower educational level (OR 11.720 ((95% CI 1.006–2.938), P <0.001), and distance more than 10km from health facility (OR: 1.631 ((95% CI (10.858–3.101), P = 0.001). Conclusion In this review, we identified a substantial treatment seeking delay among TB patients in Ethiopia. And, the independent predictors of delay were treatment sought before formal health care provider, residence of the patient, type of TB, educational level, and distance from a health facility. Thus, we recommend health extension workers, health professionals and other stakeholders to focus on patient education, and to continuously mobilize the whole communities on early treatment seeking with a special emphasis given to where treatment sought before formal health care provider, rural resident, extra pulmonary TB, and a patient living farther than 10km distance from health facility.

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Section: Introductionmentioning

confidence: 99%

Treatment seeking delay and associated factors among tuberculosis patients attending health facility in Ethiopia from 2000 to 2020: A systematic review and meta analysis

et al. 2021

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“…The main tool of the SINAN database is the notification/investigation form that includes both individual data of the patients as well as epidemiological and follow-up data until the end of treatment, on average 6 to 9 months. This information must be sent regularly from the local health units, since the municipality level, to the Ministry of Health, in order to produce the TB monitoring bulletin [21,22].…”

Section: Study Definitionsmentioning

confidence: 99%

Factors associated with death in patients with tuberculosis in Brazil: Competing risks analysis

et al. 2020

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This study aimed to analyze the factors associated with likely TB deaths, likely TB-related deaths and deaths from other causes. Understanding the factors associated with mortality could help the strategy to End TB, especially the goal of reducing TB deaths by 95% between 2015 and 2035. Methods A retrospective, population-based cohort study of the causes of death was performed using a competing risk model in patients receiving treatment for TB. Patients had started TB treatment in Brazil 2008-2013 with any death certificates dated in the same period. We used three categories of deaths, according to ICD-10 codes: i) probable TB deaths; ii) TB-related deaths; iii) deaths from other causes. Results In this cohort, 39,997 individuals (14.1%) died, out of a total of 283,508 individuals. Of these, 8,936 were probable TB deaths (22.4%) and 3,365 TB-related deaths (8.4%), illustrating high mortality rates. 27,696 deaths (69.2%) were from other causes. From our analysis, factors strongly associated with probable TB deaths were male gender (sHR = 1.33, 95% CI:

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“…Segundo Giergowicz & Mahmud (2020) no Brasil em 2014, o Sistema de Informação de Agravos de Notificação (SINAN) registrou 88.450 casos, dos quais 73.835 na forma pulmonar, 11.844 na forma extrapulmonar, e 2.720 pulmonar e extrapulmonar simultaneamente. O índice de mortalidade de 2013 foi por volta de 2,3 óbitos por 100 mil habitantes, inferior aos 2,9 óbitos por 100 mil habitantes apontados em 2003 (Jacobs & Pinto Junior, 2020). Ainda neste contexto, segundo a Fundação Oswaldo Cruz, em 2013 no Brasil, a tuberculose permanece como quarta causa de morte por doenças infectocontagiosas e a primeira causa quando relacionado à infecção pelo Vírus da Imunodeficiência Humana (HIV) (Oliveira, et al, 2021).…”

Section: Introductionunclassified

Assistência farmacêutica e acompanhamento farmacoterapêutico em populações chaves acometidas por tuberculose: uma revisão integrativa de literatura

Tananta

Lopes

Santos

et al. 2021

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Esta revisão teve como objetivo apresentar a importância do assistência farmacêutica e acompanhamento farmacoterapêutico pelo profissional farmacêutico com relação as populações chaves acometidos com tuberculose. Trata-se de uma Revisão Integrativa da Literatura (RIL), sobre a assistência farmacêutica relacionada ao serviço desenvolvido pelo profissional farmacêutico. As fontes de estudos utilizadas, foram compiladas a partir das seguintes bases de dados: Biblioteca Virtual de Saúde, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Scientific Electronic Library Online. A amostra desta RIL ficou então composta por um total de 13 artigos originais que preenchem os critérios previamente determinados pelo estudo, que descrevem de forma objetiva e atualizada sobre o tema. No que diz respeito às bases de dados, (9) pertenciam ao SciELO, (1) BVS, (3) LILACS. Mais um dado interessante, pois mostra a prevalência do SciELO. A assistência farmacêutica foi considerado como imprescindível para a promoção da qualidade de vida dos usuários de antirretrovirais, por meio de um acompanhamento com orientações, esclarecimentos de dúvidas, escuta ativa, apoio, aconselhamento e monitorização do tratamento farmacológico para o uso racional dos medicamentos. Espera-se que os resultados encontrados possam nortear ações para melhorias na qualidade dos serviços prestados pelos farmacêuticos diante da TB e gerar reflexões sobre o papel desse profissional no acompanhamento do paciente com tal enfermidade.

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Caracterização da tuberculose drogarresistente no Brasil, 2014*

Cited by 7 publications

References 18 publications

Treatment seeking delay and associated factors among tuberculosis patients attending health facility in Ethiopia from 2000 to 2020: A systematic review and meta analysis

Treatment seeking delay and associated factors among tuberculosis patients attending health facility in Ethiopia from 2000 to 2020: A systematic review and meta analysis

Factors associated with death in patients with tuberculosis in Brazil: Competing risks analysis

Assistência farmacêutica e acompanhamento farmacoterapêutico em populações chaves acometidas por tuberculose: uma revisão integrativa de literatura

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