Optimization of Acid Hydrolysis of Myricetin-3-O-rhamnoside Using Response Surface Methodology

Tolosa, Tatiana C.; Rogez, Hervé; Silva, Evaldo Martins da; Souza, Jesus Nazareno Silva de

doi:10.21577/0103-5053.20180125

Cited by 5 publications

(2 citation statements)

References 25 publications

(32 reference statements)

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“…Chemical synthesis of myricetin process can form myricetin as the final product by the steps such as hydrolysis, demethylation, methylation by using other constituents [ 52 , 97 , 103 ]. Tolosa et al reported an optimized acid hydrolysis of myricetin-3- O -rhamnoside to yield myricetin [ 111 ]. Table 1 shows content of myricetin and its glycosides in fruits, vegetables, and plant parts.…”

Section: Source Of Myricetinmentioning

confidence: 99%

Myricetin: a Multifunctional Flavonol in Biomedicine

Agraharam

Girigoswami

2022

Curr Pharmacol Rep

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Purpose of Reveiw The root cause of many diseases like CVD, cancer, and aging is free radicals which exert their effect by interfering with different metabolic pathways. The sources of free radicals can be exogenous, like UV rays from sunlight, and endogenous due to different metabolic by-products. In our body, there are defense mechanisms present, such as antioxidant enzymes and antioxidant molecules to combat these free radicals, but if there is an overload of these free radicals in our body, the defense system may not be sufficient to neutralize these free radicals. In such situations, we are exposed to a chronic low dose of oxidants creating oxidative stress, which is responsible for eliciting different diseases. Recent Findings Pubmed and Google Scholar are the search engines used to sort out relevant papers on myricetin and its role in combating many diseases. Myricetin is present in many fruits and vegetables and is a known antioxidant. It can elevate the antioxidant enzyme levels; reduces the lipid peroxidation; and is known to protect against cancer. In the case of myocardial dysfunction, myricetin has been shown to suppress the inflammatory cytokines and reduced the mortality rate. Myricetin has also been found to reduce platelet aggregation and control the viral infections by interfering in the DNA replication pathways. Summary In this paper, we have briefly reviewed about the different type and site of free radicals and the role of myricetin in addressing the ROS and different diseases.

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Section: Source Of Myricetinmentioning

confidence: 99%

Myricetin: a Multifunctional Flavonol in Biomedicine

Agraharam

Girigoswami

2022

Curr Pharmacol Rep

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“…Response surface methodology (RSM) was performed for process optimization. The empirical model of the optimum reaction parameters was calculated using suitable modeling techniques [23][24][25]. Figure 1 presents the XRD patterns of all four zeolites used as the catalyst in the ethanol conversion.…”

Section: Introductionmentioning

confidence: 99%

Application of Response Surface Methodology for Ethanol Conversion into Hydrocarbons Using ZSM-5 Zeolites

et al. 2019

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The ethanol conversion into hydrocarbons (light olefins and aromatics) using alkali-treated HZSM-5 with different SiO2/Al2O3 ratios (23, 38, and 53) zeolites was evaluated. The desilicated SAR 38 zeolite exhibited significant growth on the external surface area (61–212 m2/g) and the mesopore volume (0.07–0.37 cm3/g) without significate reduction on XRD crystallinity (93%). All catalysts were active on the ethanol conversion into hydrocarbons. At the same set of variables, the alkali-treated HZSM-5 zeolites showed a better conversion and a high selectivity to C4–C9 hydrocarbons when compared to the parent microporous zeolites. Only the parent HZSM-5 zeolite (SAR 53) was chosen for the statistical study using the standard response surface methodology in combination with the central composite design. It was found that maximum BTEX (benzene, toluene, ethylbenzene, and xylenes) and minimum ethylene production were reached for the following conditions: temperature 450 °C, pressure 20 bar, and WHSV (weight hourly space velocity) 5 h−1.

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Antioxidant and prooxidant activity of acid‐hydrolyzed phenolic extracts of sugar beet leaves in oil‐in‐water emulsions

Ebrahimi,

Bayram,

Lante

et al. 2024

J Americ Oil Chem Soc

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This study aimed to enhance the oxidative stability of soybean oil‐in‐water emulsions using acid‐hydrolyzed and unhydrolyzed extracts obtained from sugar beet leaves. The optimum extraction process, which includes 8 min of ultrasonication followed by a 2‐h acid hydrolysis, released new phenolics (e.g., catechin, myricetin, etc.) and increased the total phenolic content (TPC) from 586.24 ± 11.45 to 982.42 ± 6.61 μmol gallic acid equivalent (GAE)/L, and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) radical inhibition from 46.63 ± 1.39 to 60.87 ± 1.12%. Acid hydrolysis increased the cupric chelating activity of the extracts while decreasing ferrous chelating activity and trans‐ferulic acid concentration significantly (p < 0.05). The acid‐hydrolyzed extract at a TPC of 100 μmol GAE/L prolonged the lag phase of hexanal accumulation in the emulsion from 0 to 8 days, while 400 μmol GAE/L TPC of unhydrolyzed extract increased the lag phase to 12 days. The results show that acid‐hydrolyzed extracts in high concentrations may act as prooxidants.

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Optimization of Acid Hydrolysis of Myricetin-3-O-rhamnoside Using Response Surface Methodology

Cited by 5 publications

References 25 publications

Myricetin: a Multifunctional Flavonol in Biomedicine

Myricetin: a Multifunctional Flavonol in Biomedicine

Application of Response Surface Methodology for Ethanol Conversion into Hydrocarbons Using ZSM-5 Zeolites

Antioxidant and prooxidant activity of acid‐hydrolyzed phenolic extracts of sugar beet leaves in oil‐in‐water emulsions

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