Multifocal cutaneous Rosai-Dorfman disease masquerading as lupus vulgaris in a child

Cutaneous Rosai‐Dorfman disease in a 3‐year‐old boy

“…CRDD is extremely rare in children; as of 2020, only 10 cases had been published in the pediatric population (Table 1). 4‐13 …”

“…3 CRDD is extremely rare in children; as of 2020, only 10 cases had been published in the pediatric population (Table 1). [4][5][6][7][8][9][10][11][12][13] The etiology of CRDD is unknown. It is hypothesized that an inflammatory process, usually a viral infection, induces cell-mediated immune dysregulation and subsequent macrophage activation.…”

Persistent Cutaneous Papules and Nodules in a Six-year-old Child: A Quiz

“…However, the current patient was only 6 years old. Cutaneous RDD in children is thus extremely rare, and, to our knowledge, only 6 cases have been reported previously ( 7 ).…”

“…The indication for treatment in cutaneous RDD is often due to symptomatic lesions or systemic progression. Different treatment options have been reported, such as excision of lesions, topical steroids, retinoids, thalidomide, alkylating agents, radiotherapy or “wait-and-watch” therapy ( 6 , 7 ). The response to treatment is variable, but most patients experience resolution of their lesions ( 7 , 8 ).…”

“…Different treatment options have been reported, such as excision of lesions, topical steroids, retinoids, thalidomide, alkylating agents, radiotherapy or “wait-and-watch” therapy ( 6 , 7 ). The response to treatment is variable, but most patients experience resolution of their lesions ( 7 , 8 ). This patient was treated symptomatically with topical steroid (group 3) and frequent follow-up visits, and the parents were informed about the likely benign nature of the diagnosis of cutaneous RDD.…”