Cutaneous Rosai‐Dorfman disease in a 3‐year‐old boy

Abstract

The cutaneous form of Rosai-Dorfman disease is very rare in childhood. The clinical spectrum is highly variable and histopathological study with immunohistochemistry is essential for the diagnosis. We present the case of a 3-year-old boy with the diagnosis of cutaneous Rosai-Dorfman disease and review the pediatric cases published in the literature.

Bruised nodule on the leg of a teen

“…2 Although very rare in children, CRDD including multifocal forms 3 has been described in pediatric patients. 4,5 Histopathology revealing histiocytic infiltration with emperipolesis is a useful non-pathognomonic clue for the diagnosis of RDD. Emperipolesis may be subtler in extranodal sites, such as in CRDD, for which typical features include significant fibrosis, plasma cells infiltration, and spindled histiocytes in a storiform pattern.…”

“…Lorena Alexandra Mija MD 1 Nelson Piche MD 2 Viktor Kokta MD 3 Josee Dubois MD 4 Jerome Coulombe MD 5 1…”

“…One study reported a predilection for the extremities 2 . Although very rare in children, CRDD including multifocal forms 3 has been described in pediatric patients 4,5 …”