Case for diagnosis. Patch granuloma annulare

Magalhães, Geraldo Magela; Guimarães, Cássio Ferreira; Paula, Maysa Carla de

doi:10.1590/abd1806-4841.20176729

Cited by 7 publications

(2 citation statements)

References 11 publications

(13 reference statements)

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“…Se presenta como máculas eritematosas, pardas o violáceas, no infiltradas, de forma redondeada u ovoidea, con configuración anular o sin ella, únicas o múltiples, de crecimiento centrífugo. Se localiza mayoritariamente en la región proximal de los miembros y rara vez compromete las palmas y las plantas 17 . Puede presentar o no descamación.…”

Section: Discussionunclassified

“…Las fibras elásticas aisladas aleatoriamente alternan con fibras normales, rodeadas de los histiocitos y los depósitos de mucina. Menos a menudo, se puede encontrar el patrón en empalizada, caracterizado por un núcleo central de colágeno degenerado, rodeado radialmente por el infiltrado de linfocitos, histiocitos y fibroblastos, fagocitosis de fibras elásticas por células gigantes en la periferia y depósitos de mucina 2,3,4,9,11,17 .…”

Section: Discussionunclassified

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Granuloma anular maculoso

Juárez¹,

Gallmann²,

Brusa³

et al. 2021

Dermatol. Argent.

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El granuloma anular maculoso es una variante rara de granuloma anular, que representa un desafío diagnóstico. Su incidencia se desconoce y se presenta con mayor frecuencia en las mujeres de entre 40 y 70 años. Se asocia a las mismas entidades y responde a los mismos tratamientos que las otras variantes clínicas de granuloma anular. Se presentan los casos de 5 mujeres con diagnóstico de granuloma anular maculoso, que recibieron diferentes tratamientos tópicos y sistémicos, con respuestas clínicas variables.

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Section: Discussionunclassified

Granuloma anular maculoso

Juárez¹,

Gallmann²,

Brusa³

et al. 2021

Dermatol. Argent.

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Patch granuloma annulare of the legs

et al. 2019

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Patch‐type granuloma annulare: An institution‐based study of 23 cases

Khanna

North

2020

J Cutan Pathol

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BackgroundGranuloma annulare (GA) is a skin disorder of uncertain etiology. Patch (type) GA is an uncommon variant of GA with a paucity of data characterizing it. We describe the features of 23 cases of patch GA.MethodsThe archives of dermatopathology were searched for cases of patch GA. The clinical history and morphology for each patient were reviewed. Only cases with patch clinical morphology were included. The clinical and histopathologic features were assessed including the pattern of granulomatous inflammation and presence of other inflammatory cell types.ResultsMost patients were female (19/23) with erythematous patches on the trunk and proximal extremities. The most common clinical differential diagnosis included mycosis fungoides (MF), morphea and contact dermatitis. Dyslipidemia was the most common comorbidity (30%), followed by diabetes (15%) and hypertension (15%). Histopathologic features included interstitial lymphocytes and histiocytes with dermal mucin. Two cases showed focal palisaded granulomas. Eosinophils and plasma cells were present in 1/3 of cases.ConclusionPatch GA is an uncommon GA variant with an interstitial granulomatous histopathologic pattern that predominantly affects women over 50. It can mimic interstitial MF and early morphea both clinically and histopathologically. Awareness of this GA variant can help prevent misdiagnosis and inappropriate treatment for these patients.

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Case for diagnosis. Patch granuloma annulare

Cited by 7 publications

References 11 publications

Granuloma anular maculoso

Granuloma anular maculoso

Patch granuloma annulare of the legs

Patch‐type granuloma annulare: An institution‐based study of 23 cases

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