Determination of the critical hydrophile-lipophile balance of licuri oil from Syagrus coronata: application for topical emulsions and evaluation of its hydrating function

Leal, Leila Bastos; Sousa, Giovana Damasceno; Seixas, Karoline Belém; Souza, Pedro Henrique Nogueira de; Santana, Davi Pereira de

doi:10.1590/s1984-82502013000100018

Cited by 16 publications

(13 citation statements)

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“…The formulations studied had the pH adjusted to slightly acidic values, as this was the ideal pH range (5.5-6.5) for the proposed purposes, and also to optimize the viscosity of the polymer used. The formulations showed well-formed droplets with small size variation, thus indicating greater stability of the emulsified system [11].…”

Section: Physicochemical Characterization Of the Creamsmentioning

confidence: 93%

New Oils for Cosmetic O/W Emulsions: In Vitro/In Vivo Evaluation

et al. 2018

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Abstract:The aim of this study was to design new cosmetic formulations containing oils from catolé, licuri and spent coffee grounds, and to evaluate their immediate and long-term effects on skin barrier function and skin hydration. Nonionic oil-in-water (o/w) emulsions were prepared and physicochemically characterized. The effects of the formulations were assessed by volunteers and by measuring the water content of the epidermis (WCE) and transepidermal water loss (TEWL) both two hours and 20 days after daily application. The irritation potential was evaluated using three different methods: the Hen's egg chorioallantoic membrane test (HET-CAM); the observation of undesirable effects after skin formulation application, and by using the L*a*b* system to verify changes in skin coloring. The results obtained showed that the formulations containing 10% of these oils presented promising characteristics in the improvement of hydration and skin barrier function when compared to the baseline values and with the placebo cream. According to the sensory evaluation performed, all creams were found to have great acceptability.

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Section: Physicochemical Characterization Of the Creamsmentioning

confidence: 93%

New Oils for Cosmetic O/W Emulsions: In Vitro/In Vivo Evaluation

et al. 2018

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“…Healthy skin is determined mainly by percutaneous absorption, plasticity, and cellular renovation [1]. During the aging process, there is a lack of organization of these characteristics along with the loss of its antioxidant defense capacity, which causes an imbalance in the epithelium, resulting in an increase of free radical levels [1,2].…”

Section: Introductionmentioning

confidence: 99%

“…During the aging process, there is a lack of organization of these characteristics along with the loss of its antioxidant defense capacity, which causes an imbalance in the epithelium, resulting in an increase of free radical levels [1,2]. Currently, these factors are considered the main causes of the aging process.…”

Section: Introductionmentioning

confidence: 99%

“…Such a process is related to the molecular arrangement, the physicochemical properties of the active pharmaceutical ingredients (API), and the vehicle used in the formulation. In this context, one of the molecules that has been a current target of research in the cosmetic field is resveratrol [1][2][3][4]. Resveratrol (3,4,5-trihydroxy-trans-stilbene) is a natural phenolic compound produced by some spermatophyte species in response to attacks by pathogens or exposure to ultraviolet radiation or ozone.…”

Section: Introductionmentioning

confidence: 99%

“…Among the different cosmetics produced, emulsions are widely used to incorporate incompatible cosmetic components [1]. Despite the existence of some commercial products containing resveratrol, there are no studies on its incorporation into emulsions made with liotropic liquid crystals [4,[6][7][8].…”

Section: Introductionmentioning

confidence: 99%

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Cosmetic Potential of a Liotropic Liquid Crystal Emulsion Containing Resveratrol

Oliveira

et al. 2017

Cosmetics

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Abstract:Resveratrol is a natural substance that has been the target of many researchers over the years since it presents a variety of potential applications in the areas of cosmetics and medicine as a treatment for some diseases. Due to its high antioxidant capacity but low bioavailability, we evaluated the antiaging potential of resveratrol as a liotropic liquid crystal emulsion. Initially, we performed in vitro assays to quantify both the organoleptic characteristics and stability of the emulsion. Next, an in vivo trial was performed on the faces of 30 volunteers to determine the cream's cosmetic potential and to measure porphyrins, skin barrier function, skin pigmentation, expression lines, and porosity. The emulsion maintained its characteristics during the in vitro assays and, in the in vivo trial, it had some effect only on pore size in forehead, without any significant effects on the other parameters. We had 6 dropouts throughout the study, then the final number of volunteers was 24. Most volunteers did not show any changes in skin pigmentation throughout the study. Similarly, there was not any noticeable improvement on any other parameters evaluated. However, volunteers related a high level of satisfaction with the product.

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