Glucose levels and hemodynamic changes in patients submitted to routine dental treatment with and without local anesthesia

Bortoluzzi, Marcelo Carlos; Manfro, Rafael; Nardi, Anderson

doi:10.1590/s1807-59322010001000009

Cited by 12 publications

(15 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This results were also in agreement with many other studies like Bortoluzzi et al, (2010) [18] who explained results with regard to adrenaline and adrenergic system stimulation. It might be that adrenaline has both β1 and β2 activity.…”

Section: Discussionsupporting

confidence: 93%

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Al-Saffar¹,

Al–Sandook²,

Taha³

2014

AJPS

View full text Add to dashboard Cite

Aim: To study the effects of local anesthesia on blood pressure in patients undergo extraction of maxillary teeth under infiltration local anesthesia and to compare the level of salivary chromogranin A before and after administration of local anesthesia and its possible correlation with hemodynamic effects of local anesthesia. Materials and Methods: A total of 26 patients (18 female, 8 male) who need tooth extraction under infiltration local anesthesia were examined in two situations (pre and post local anesthetic administration). For each patient salivary sample was collected by salivette to estimate the level of chromogranin A using ELISA Kits. For all patients, the blood pressure and pulse rate were measured before and after administration of local anesthesia using automatic blood pressure recorder. Results: the results showed significant differences between salivary chromogranin A for patients before the administration of local anesthesia (580.33 ± 130.42) ng/ml and after the administration of local anesthesia (674.51+ 130.93) ng/ml with p < 0.05. The results also showed that the mean value of blood pressure (systolic and diastolic blood pressure) lowered after administration of local anesthesia but with no significant differences (p > 0.05) with pre -local anesthetic value. The pulse rate was increase in it is value after local anesthetic administration with a significant differences (p < 0.05) than pre -anesthetic value. Conclusions: tooth extraction and administration of infiltration local anesthesia caused hypotension with no significant effect (p > 0.05) while it caused increase in pulse rate with a significant effect (p < 0.05). Administration of infiltration local anesthesia caused significant effects on salivary chromogranin A levels, also this study showed that there was significant inverse correlation between systolic blood pressure and chromogranin A levels(p < 0.05) after administration of infiltrations local anesthesia during dental treatments (tooth extraction).

show abstract

Section: Discussionsupporting

confidence: 93%

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Al-Saffar¹,

Al–Sandook²,

Taha³

2014

AJPS

View full text Add to dashboard Cite

show abstract

“…Moreover, the use of anesthetic solutions lacking vasoconstrictors might increase the risk of cardiac diseases due to the potential pain caused by insufficient anesthesia. (Ezmek et al, 2010;Bortoluzzi, Manfro, & Nardi, 2010;Conardo et al, 2007) Lidocaine is one of the most commonly used anesthetics that has good pharmacokinetics and a lower toxicity compared to other amidic anesthetics and is therefore appropriate for use in dental procedures (de Morias et al, 2012). Although the use of two 1.8 mg cartridges of local anesthetics containing 1:100,000epinephrine in patients with controlled blood pressure and those with mild blood pressure (ASA I, i.e.…”

Section: Introductionmentioning

confidence: 99%

Comparative Assessment of the Effects of Three Local Anesthetics: Lidocaine, Prilocaine, and Mepivacaine on Blood Pressure Changes in Patients with Controlled Hypertension

Hashemi¹,

Ladez²,

Moghadam³

2016

GJHS

View full text Add to dashboard Cite

Background: Given large number of patients with hypertension attending dental clinics and the profound effects of local anesthetics containing vasoconstrictors, this study aimed to compare the effects of lidocaine 2% + epinephrine, prilocaine 3% + felypressin0.03, and mepivacaine 3% on blood pressure changes. Methods:The current study was carried out from May 2014 to February 2015.Patients with controlled hypertension (systolic blood pressure<159.94 mmHg before the injection) who attended Zahedan dental school (Zahedan , Iran) for the extraction of a mandibular tooth were selected and randomly allocated to three groups of 20. Groups 1-3 received lidocaine 2% + epinephrine, prilocaine 3% + felypressin 0.03 units, and mepivacaine3%, respectively. Patients were only included if they were injected with a maximum of two 1.8 ml cartridges (3.6 ml) for tooth extraction (maximum epinephrine dose of 0.04 mg was maintained in systemic patients).The collected data were analyzed using the analysis of variance (ANOVA) in SPSS 19.0. (SPSS Inc., Chicago, IL, USA)Results: No significant differences were observed between the systolic and diastolic blood pressure of the three groups. The three evaluated local anesthetic solutions had similar effects in patients with controlled hypertension. Conclusion:While no significant changes in blood pressure were observed in three groups, all dental procedures on the mentioned group of patients have to be performed under careful monitoring and aspiration. Moreover, the maximum epinephrine dose (0.04mg) should never be exceeded in these patients.

show abstract

“…Outra pesquisa avaliou alterações hemodinâmicas e glicêmicas em 37 pacientes que foram tratados com anestésico local associado a um vasoconstrictor ou sem anestesia local (mepivacaína 2% com adrenalina 1:100.000). Os pacientes que receberam o anestésico com vasoconstrictor adrenérgico não apresentaram mudanças glicêmicas estatisticamente significantes 21 . Em suma, estudos sustentam que nos pacientes compensados o uso de anestésico com vasoconstrictor adrenérgico é permitido.…”

Section: Particularidades Sobre O Uso De Fármacos Em Pacientes Diabétunclassified

O Paciente Diabético na Clínica Odontológica: Diretrizes Para o Acolhimento e Atendimento

Costa¹,

Teixeira²,

Azoubel³

et al. 2016

Rev. bras. ciênc. Saúde

View full text Add to dashboard Cite

Professora Assistente do componente curricular Estomatologia II na EBMSP, Salvador, Bahia, Brasil. 1 2 3 4 RESUMO Introdução: Diabetes Mellitus é um grupo de doenças metabólicas que vem se tornando cada vez mais frequente na população mundial, sendo considerado um problema de saúde pública. Essa patologia pode apresentar na cavidade bucal suas primeiras manifestações, predispondo o paciente a várias alterações bucais. O cirurgião-dentista necessita conhecer a doença e conduzir um correto manejo desses pacientes. Objetivo: Propor um protocolo de atendimento e manejo odontológico para pacientes diabéticos. Desenvolvimento: Na anamnese, reunir informações sobre a doença: tipo, tempo de diagnóstico, farmacoterapia, manifestações sistêmicas e bucais, histórico de crise hipoglicêmica ou hiperglicêmica. Ao exame físico, atentar para verificação de sinais vitais, índice de massa corporal, avaliação de tecidos moles e preenchimento do odontograma e periograma. Avaliar hemoglobina glicada de pacientes previamente diagnosticados e encaminhar pacientes com suspeita para o médico. No dia da consulta, recomendar que o paciente se alimente normalmente e realize o uso de suas medicações. As consultas devem ser curtas, no início da manhã e glicosimetria deve ser realizada no início do atendimento. Pacientes compensados prescindem o uso de antibioticoprofilaxia e podem receber anestésico com vasoconstrictor adrenérgico. Em casos de urgência por crise hipoglicêmica, a mesma deve ser solucionada antes de torna-se uma emergência médica. Conclusão: Com exame clínico e complementares, coletar o máximo de informações sobre a doença para classificar o paciente em relação ao risco que apresenta ao atendimento. Pacientes compensados não necessitam de tratamento odontológico diferenciado. Pacientes descompensados não devem sofrer nenhum tratamento eletivo e devem ser tratados de acordo com as limitações presentes.

show abstract

Glucose levels and hemodynamic changes in patients submitted to routine dental treatment with and without local anesthesia

Cited by 12 publications

References 14 publications

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Comparative Assessment of the Effects of Three Local Anesthetics: Lidocaine, Prilocaine, and Mepivacaine on Blood Pressure Changes in Patients with Controlled Hypertension

O Paciente Diabético na Clínica Odontológica: Diretrizes Para o Acolhimento e Atendimento

Contact Info

Product

Resources

About