Pleomorphic Undifferentiated Sarcoma of the Penis

Hayek, Omar; Ibrahim, Roberto El; Lemos, Gustavo Caserta

doi:10.1590/s1807-59322008000600022

Cited by 4 publications

(4 citation statements)

References 3 publications

(2 reference statements)

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“…It occurs more commonly in the extremities, and cases of primary undifferentiated pleomorphic sarcoma of the penis are very difficult to find. 9 El Hayek and colleagues 10 suggest that one possible explanation could be the occurrence of de-differentiation. On the other hand, the tumour could have been pleomorphic from the start.…”

Section: Discussionmentioning

confidence: 99%

Pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma of the glans penis

Seo

Chuluun

et al. 2013

CUAJ

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Primary sarcoma of the penis has an extremely low incidence, and its diagnosis and treatment are unclear. A 55-year-old man presented with an oval-shaped mass of the glans penis, which was treated by a wide excision. The pathologic result revealed an undifferentiated high-grade sarcoma, which was diagnosed as a pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma based on the World Health Organization classification. There was no recurrence at the12-months postoperative follow-up.

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Section: Discussionmentioning

confidence: 99%

Pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma of the glans penis

Seo

Chuluun

et al. 2013

CUAJ

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“…In that case, the patient had local and systemic progression to adjacent fat tissue and pulmonary and hepatic nodules despite total penectomy, systemic chemotherapy, and radiation therapy. He died 17 months after the initial diagnosis of the disease ( Table 1 ) [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…Other types are much more rare [ 3 ]. Sixteen cases of epithelioid sarcomas and only 1 case of undifferentiated sarcoma have so far been documented in the English language literature [ 1 , 4 ]. Here we report the case of a 16-year-old boy, the youngest penile sarcoma patient ever recorded, with a brief review of the literature.…”

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confidence: 99%

Primary Undifferentiated Penile Sarcoma in Adolescence

et al. 2012

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We report a case of primary penile undifferentiated sarcoma. A 16-year-old adolescent man visited Pusan National University Hospital complaining of a painless mass on his penis that was increasing in size. Magnetic resonance images revealed a 5×5-cm mass and pathological examinations revealed small round cell sarcomas with neuroendocrine differentiation. The tumor, which had metastatic pulmonary nodules, was treated by tumorectomy and systemic chemotherapy. Thirty-four months after the initial diagnosis, the patient was still alive without evidence of local recurrence or metastatic disease. This is our second case of an undifferentiated penile sarcoma.

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“…Primary undifferentiated pleomorphic sarcoma of the penis is extremely rare, with only 4 cases reported in English literature and essentially represents a diagnosis of exclusion. The average tumor size was 5 cm and prognosis was associated with local recurrence and progression distance [7,9,19,20].…”

Section: Management and Outcomesmentioning

confidence: 99%

Primary Radiation-Induced Sarcoma of the Penis: Case Report and Review of the Literature

Arenas¹,

Guillermo²,

Julian³

et al. 2022

Int Arch Urol Complic

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Introduction: Primary penile sarcoma has an incidence of 0.6 in 100,000 patients in developed countries. Risk factors such as radiotherapy have been identified, which can generate mutagenesis of the irradiated tissue adjacent to the irradiation field. Given the increase in survival of patients that received radiotherapy, the incidence of radio-induced sarcomas has increased. We report the first documented case in Latin America of radio-induced undifferentiated sarcoma of the penis. Materials and Methods:Case report and literature review. Results:We report the case of an 89 year-old male patient, who consulted due to a 9-month history of intermittent urethrorrhagia, penile pain and priapism. It is noteworthy that he received radiotherapy for prostate adenocarcinoma. Ultrasound and MRI of the pelvis confirmed a tumor dependent on the right corpus cavernosum, and it was decided to take a biopsy of the mass. Biopsy of the lesion showed a high-grade undifferentiated sarcoma. He underwent radiotherapy and surgery, he had an unfavorable evolution and died shortly after. Conclusion:Radio induced sarcomas of the penis are rare and usually have a poor prognosis due to delayed diagnosis. Its early diagnosis is difficult because the initial symptomatology is nonspecific, very similar, for example, to that of Peyronie's disease. Thus, a suspicion and timely identification can impact the prognosis of these neoplasms.

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Pleomorphic Undifferentiated Sarcoma of the Penis

Cited by 4 publications

References 3 publications

Pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma of the glans penis

Pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma of the glans penis

Primary Undifferentiated Penile Sarcoma in Adolescence

Primary Radiation-Induced Sarcoma of the Penis: Case Report and Review of the Literature

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