Incidência de TB diagnosticada no pronto-atendimento de um hospital escola na região sudeste do Brasil

Miranda, Silvana Spíndola de; Toledo, Ana Rita de Paiva; Ribeiro, Simone Rodrigues; Campos, Izabella Maria Ferreira; Sthur, Petra Maria de Oliveira Duarte; Kritski, Afrânio Lineu

doi:10.1590/s1806-37132009000200011

Cited by 2 publications

(1 citation statement)

References 7 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In isolation, Streptomycin and Isoniazid were less effective, both presenting five strains resistant. Studies [12,13,14,15,16] confirm isoniazid to be less effective against M. tuberculosis. By these studies, STR was more effective than INH.…”

Section: Discussionmentioning

confidence: 99%

Inhibition of drug-sensitive and drug-resistant Mycobacterium tuberculosis strains by essential oil from Croton argyrophylloides Mull. Arg.

Alves

Nunes²,

Fakhouri³

et al. 2016

Int Arch Med

View full text Add to dashboard Cite

Objective: To assess in vitro effects of essential oil extracted from Croton argyrophylloides against clinical and standard strains of Mycobacterium tuberculosis, comparing its resistance and sensitivity profiles to drugs commonly used in therapy. Method: In the present study, chemical composition and antimycobacterial activity of essential oils extracted from aerial parts of Croton argyrophylloides collected in Curituba district, Sergipe, Brazil were analysed. The oil was studied by GC and GC-MS and its antimicobacterial activity (MIC) was tested against 49 clinical and standard covers H 37 Rv using the REMA method. To access sensitivity to isoniazid, rifampicin, ethambutol and streptomycin it was used proportions indirect test method. Results: Twenty-seven chemicals were identified, totalizing 95.98% of the composition of essential oil. The oil presented good antibacterial activity (MIC = 97 to 195 g / ml) against strains of Mycobacterium tuberculosis H 37 Rv and pattern one. Conclusion: On pharmacological activities of these species confirmed in vitro scientific support for its use in traditional herbal preparations.

show abstract

Section: Discussionmentioning

confidence: 99%

Inhibition of drug-sensitive and drug-resistant Mycobacterium tuberculosis strains by essential oil from Croton argyrophylloides Mull. Arg.

Alves

Nunes²,

Fakhouri³

et al. 2016

Int Arch Med

View full text Add to dashboard Cite

show abstract

Provider initiated tuberculosis case finding in outpatient departments of health care facilities in Ghana: yield by screening strategy and target group

Ohene

Bonsu²,

Hanson-Nortey³

et al. 2017

BMC Infect Dis

View full text Add to dashboard Cite

BackgroundMeticulous identification and investigation of patients presenting with tuberculosis (TB) suggestive symptoms rarely happen in crowded outpatient departments (OPDs). Making health providers in OPDs diligently follow screening procedures may help increase TB case detection. From July 2010 to December 2013, two symptom based TB screening approaches of varying cough duration were used to screen and test for TB among general outpatients, PLHIV, diabetics and contacts in Accra, Ghana.MethodsThis study was a retrospective analysis comparing the yield of TB cases using two different screening approaches, allocated to selected public health facilities. In the first approach, the conventional 2 weeks cough duration with or without other TB suggestive symptoms was the criterion to test for TB in attendants of 7 general OPDs. In the second approach the screening criteria cough of >24 hours, as well as a history of at least one of the following symptoms: fever, weight loss and drenching night sweats were used to screen and test for TB among attendants of 3 general OPDs, 7 HIV clinics and 2 diabetes clinics. Contact investigation was initiated for index TB patients. The facilities documented the number of patients verbally screened, with presumptive TB, tested using smear microscopy and those diagnosed with TB in order to calculate the yield and number needed to screen (NNS) to find one TB case. Case notification trends in Accra were compared to those of a control area.ResultsIn the approach using >24-hour cough, significantly more presumptive TB cases were identified among outpatients (0.82% versus 0.63%), more were tested (90.1% versus 86.7%), but less smear positive patients were identified among those tested (8.0% versus 9.4%). Overall, all forms of TB cases identified per 100,000 screened were significantly higher in the >24-hour cough approach at OPD (92.7 for cough >24 hour versus 82.7 for cough >2 weeks ), and even higher in diabetics (364), among contacts (693) and PLHIV (995). NNS (95% Confidence Interval) varied from 100 (93-109) for PLHIV, 144 (112-202) for contacts, 275 (197-451) for diabetics and 1144 (1101-1190) for OPD attendants. About 80% of the TB cases were detected in general OPDs. Despite the intervention, notifications trends were similar in the intervention and control areas.ConclusionThe >24-hour cough approach yielded more TB cases though required TB testing for a larger number of patients. The yield of TB cases per 100,000 population screened was highest among PLHIV, contacts, and diabetics, but the majority of cases were detected in general OPDs. The intervention had no discernible impact on general case notification.

show abstract

Incidência de TB diagnosticada no pronto-atendimento de um hospital escola na região sudeste do Brasil

Cited by 2 publications

References 7 publications

Inhibition of drug-sensitive and drug-resistant Mycobacterium tuberculosis strains by essential oil from Croton argyrophylloides Mull. Arg.

Inhibition of drug-sensitive and drug-resistant Mycobacterium tuberculosis strains by essential oil from Croton argyrophylloides Mull. Arg.

Provider initiated tuberculosis case finding in outpatient departments of health care facilities in Ghana: yield by screening strategy and target group

Contact Info

Product

Resources

About