Características de pacientes com câncer de pulmão na cidade de Manaus

Westphal, Fernando Luíz; Lima, Luciano Rodrigues Ornelas de; Andrade, Edson Oliveira; Netto, José Corrêa Lima; Silva, Andrei Salvioni da; Carvalho, Bruna Cecília Neves de

doi:10.1590/s1806-37132009000200009

Cited by 18 publications

(12 citation statements)

References 27 publications

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“…In general, the overall survival was better than in those who received chemotherapy in comparison to best support of care, but considerably lower than in those reported in the literature. 23 , 24 , 31 – 33 There are no data regarding maintenance therapy in the Brazilian population.…”

Section: Treatmentmentioning

confidence: 99%

Lung cancer in Brazil: epidemiology and treatment challenges

Sá

Coelho

Capelozzi

et al. 2016

LCTT

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Lung cancer persists throughout the world as a major cause of death. In 2014, data from the Brazilian National Cancer Institute (INCA) estimated 16.400 new cases of lung cancer among men (second most common) and 10.930 new cases among women (fourth most common). These data are consistent for all Brazilian regions and reflect the trends of cancer in the country over the last decade. Brazil is a continental country, the largest in Latin America and fifth in the world, with an estimated population of >200 million. Although the discrepancy in the national income between rich and poor has diminished in the last 2 decades, it is still huge. More than 75% of the Brazilian population do not have private health insurance and rely on the national health care system, where differences in standard of cancer care are evident. It is possible to point out differences from the recommendations of international guidelines in every step of the lung cancer care, from the diagnosis to the treatment of advanced disease. This review aims to describe and recognize these differences as a way to offer a real discussion for future modifications and action points toward delivery of better oncology care in our country.

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Section: Treatmentmentioning

confidence: 99%

Lung cancer in Brazil: epidemiology and treatment challenges

Sá

Coelho

Capelozzi

et al. 2016

LCTT

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“…25 However, studies in the Brazilian population have shown that SCC remains the most prevalent subtype in some areas of the country. 26 We found that the prevalence of bone metastases varied according to histology, with a higher prevalence for adenocarcinoma (35.3%; n = 67) and SCLC (31.2%; n = 15), and a lower prevalence for SCC (14.7%; n = 15). These results indicate that the probability of bone dissemination may vary according to the histology of lung tumor.…”

Section: Discussionmentioning

confidence: 79%

O impacto da histologia do carcinoma pulmonar na frequência das metástases ósseas

et al. 2019

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Objective Lung cancer is the leading cause of death by cancer, and the bones are one of the most common sites of metastasis from this condition. This study aimed to evaluate the influence of lung carcinoma histology on the frequency of bone metastases. Methods This retrospective study evaluated the medical records of 407 patients diagnosed with lung cancer between 2003 and 2012. The prevalence of bone metastases and their association with histological subtypes were evaluated using chi-squared tests, odds ratios (ORs) and 95% confidence intervals (CIs). The overall survival was evaluated using the Kaplan-Meier method. Results The prevalence of bone metastases was 28.2% ( n = 115), and the spine was the most frequently affected site (98 metastases; 32.1%). Adenocarcinoma was the most common histological subtype of lung carcinoma (46.7%), and it was significantly more frequent among patients with bone metastases (58.3% versus 42.1%; p = 0.003; OR = 1.92; 95% CI: 1.29–2.97). Squamous cell carcinoma was significantly less frequent among patients with bone metastases (13.0% versus 29.8%; p = 0.0004; OR = 0.35; 95% CI: 0.19–0.64). The median survival time after the first bone metastasis diagnosis was 4 months. Conclusion Adenocarcinoma was the most common histological subtype of lung carcinoma, and it was significantly associated with a higher risk of developing bone metastases.

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“…Men were most affected, with 23 cases of cancer, while 14 cases were observed among women. Studies in the literature report that male individuals are most affected by lung cancer, despite the increase observed in the number of cases among women in the last decades (23,24) .…”

Section: Relation Between Bronchoscopy Results and Presence/absence Omentioning

confidence: 99%

“…The medical literature clearly describes the surgical therapy as critical in the treatment of lung cancer (29) . However, studies report a small number of patients submitted to surgery and demonstrate that resectability criteria are met in only 20% of cases at the time of diagnosis (23,24,30) .…”

Section: Discussionmentioning

confidence: 99%

Estudo comparativo do diagnóstico de câncer pulmonar entre tomografia computadorizada e broncoscopia

Maximino

Saraiva

2010

Radiol Bras

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OBJETIVO: Analisar a tomografia computadorizada e a broncoscopia no diagnóstico do câncer pulmonar e verificar a eficácia destas técnicas perante a presença desta doença. Os parâmetros idade, gênero, hábitos tabágicos, tipos histológicos, estadiamento e terapêutica foram, igualmente, analisados. MATERIAIS E MÉTODOS: Foram analisados 70 pacientes do Serviço de Pneumologia do Hospital Distrital da Figueira da Foz, Coimbra, Portugal, que realizaram ambas as técnicas em estudo, tendo-se confirmado ou não a presença de câncer pulmonar. RESULTADOS: Diagnosticaram-se 37 tumores pulmonares, 23 casos no gênero masculino e 14 no feminino. Histologicamente, 40,54% eram adenocarcinomas, seguido do carcinoma escamoso (32,43% dos casos) e do carcinoma de pequenas células (18,92%). O estadiamento mostrou 6,70% no estádio IB, 23,30% no estádio IIIA comparativamente ao IIIB com 36,70%, encontrando-se 33,30% dos doentes no estádio IV. A quimioterapia isolada foi efetuada em 75,7% dos doentes. A sensibilidade da broncoscopia foi de 83,8%, a especificidade, de 81,8%, e a precisão, de 82,8%. A sensibilidade da tomografia computadorizada foi de 81,1%, a especificidade, de 63,6%, e a precisão, de 72,8%. CONCLUSÃO: Os resultados da broncoscopia confirmaram a sua importância no diagnóstico do câncer pulmonar, pela dependência deste no exame anatomopatológico do tecido ou células, obtido por várias técnicas de biópsia. A tomografia computadorizada apresentou boa sensibilidade, de 81,1%, contudo, a sua especificidade, de apenas 63,6%, resulta do número de falso-positivos (36,4%).

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Características de pacientes com câncer de pulmão na cidade de Manaus

Cited by 18 publications

References 27 publications

Lung cancer in Brazil: epidemiology and treatment challenges

Lung cancer in Brazil: epidemiology and treatment challenges

O impacto da histologia do carcinoma pulmonar na frequência das metástases ósseas

Estudo comparativo do diagnóstico de câncer pulmonar entre tomografia computadorizada e broncoscopia

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