Influência de características gerais na qualidade de vida de pacientes com doença pulmonar obstrutiva crônica

Abstract

Background: There is currently no consensus regarding which factors influence the quality of life of patients suffering from chronic obstructive pulmonary disease (COPD). However, identifying such factors could orient approaches to improving the quality of the lives of these patients.Objective: To evaluate factors that can interfere with quality of life in COPD patients selected for pulmonary rehabilitation. Methods:Twenty-one patients with moderate to severe COPD were evaluated. Maximal inspiratory pressure (MIP), 6-minute walk test (6MWT), body mass index (BMI), pulmonary function, blood gases, grip strength (measured with a dynamometer), quadriceps strength and St. George's Respiratory Questionnaire (SGRQ) scores were assessed.Results: Statistically significant negative correlations with quality of life were found for the following factors: "impact" scores of: forced expiratory volume in one second (FEV 1 ) (r = -0.68; p = 0.004), FEV 1 to forced vital capacity ratio (FEV 1 /FVC) (r = -0.61; p = 0.014), peak expiratory flow (PEF) (r = -0.53 (p = 0.015), 6MWT (r = -0.63; p = 0.001) and BMI (r = -0.64; p = 0.002); "activity" scores for: MIP (r = -0.57; p = 0.007), baseline arterial oxygen saturation by pulse oximetry (SpO 2 ) (r = -0.52; p = 0.018) and 6MWT (r = -0.58; p = 0.007); "symptom" score for: BMI (r = -0.60; p = 0.005); and "total" scores for: FEV 1 (r = -0.64; p = 0.01), PEF (r = -0.47; p = 0.033) and BMI (r = -0.57; p = 0.009). Multiple linear regression revealed the primary factors influencing quality of life to be: BMI, which presented a significant influence on "symptom", "impact" and "total" scores (p = 0.002, p = 0.009 and p = 0.024, respectively); and 6MWT, which had a significant influence on "activity" and "impact" scores (p = 0.048 and p = 0.010, respectively). Conclusions:The BMI and 6MWT were shown to have an influence on quality of life in the COPD patients studied. Therefore, therapeutic approaches to improving the quality of life of COPD patients should take these indices into consideration.

Influência dos parâmetros funcionais respiratórios na qualidade de vida de pacientes com DPOC

“…This sample size limitation has also been observed in other studies. (6,25,30) The results of this study showed that the patients presenting a reduction in FEV 1 have an impaired quality of life. This relationship becomes evident when a specific questionnaire, such as the SGRQ, is used.…”

Effects of an incremental walking test in the gait of individuals with Chronic Obstructive Pulmonary Disease

“…The study of Dourado et al 2 noted that the SpO 2 had a negative correlation with the physical activity field, suggesting that hypoxemic patients have minor physical performance capacity.…”

“…The prevalence of COPD increases gradually with age, being the leading cause of morbidity in the elderly 2 . As a result of the ageing population, the prevalence of COPD will continue to grow in the coming decades, resulting in a large economic impact [2][3][4] .…”

“…The prevalence of COPD increases gradually with age, being the leading cause of morbidity in the elderly 2 . As a result of the ageing population, the prevalence of COPD will continue to grow in the coming decades, resulting in a large economic impact [2][3][4] . In addition to pulmonary components, systemic consequences are often observed in patients with COPD, such as weight loss, malnutrition, emotional problems, muscle weakness and physical deconditioning [2][3][4][5][6][7][8] .…”

Evolução dos marcadores diagnósticos e prognósticos de pacientes com DPOC no período de três anos

“…Em nosso estudo, ao substituir o índice BODE pelo VEF 1 , IMC, MRC e DP6 na análise de regressão logística múltipla, encontramos que a variação do MRC foi preditora da piora clinicamente significativa no escore total e no domínio atividade. Em estudos transversais e longitudinais, a intensidade da dispneia é reportada como preditora da qualidade de vida (Dourado et al, 2004;Schelecht et al, 2005, Oga et al, 2007. Em estudo longitudinal, a mudança no escore total do SGRQ apresentou correlação com as mudanças na percepção de dispneia (r=0,59), avaliada pelo MRC, e também com a mudança nos valores do VEF 1 em porcentagem dos valores previstos embora com valores menores de r (r=0,44) (Oga et al, 2007).…”