Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: infecções que causam úlcera genital

Ramos, Maria Eliza Barbosa; Sardinha, José Carlos; Alencar, Herculano Duarte Ramos de; Aragón, Mayra Gonçalves; Lannoy, Leonor Henriette de

doi:10.1590/s1679-4974202100010.esp1

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…Pueden ser un signo guía de un gran abanico de entidades patológicas cutáneas o sistémicas 2 . A nivel mundial, la causa más frecuente de úlceras genitales es la infección por virus herpes simple (HSV), seguido de la sífilis y el linfogranuloma venéreo 2,3,4,5 . Los factores de riesgo del enfermo orientan al diagnóstico etiológico, por lo que es importante conocer su estado inmune 1 .…”

Section: Introductionunclassified

Úlceras genitales crónicas por virus del herpes simple en paciente inmunocomprometido: reporte de caso

Baquedano-Ordoñez

Martel-Ramos

2022

Rev Hisp Cienc Salud

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El herpes genital es una infección de transmisión sexual vírica que representa la causa más frecuente de úlcera genital. Clínicamente, cursa con episodios recurrentes, asintomáticos, o con lesiones características como vesículas-úlceras. En nuestro medio, el diagnóstico es eminentemente clínico, aunque existen pruebas laboratoriales para su confirmación, el tratamiento de elección consiste en fármacos antivirales sistémicos, que acortan el tiempo de eliminación del virus, aunque no evitan la recidiva. Además, es importante recordar su frecuente predisposición con otras ITS, en especial, el VIH/SIDA como en este caso.

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Section: Introductionunclassified

Úlceras genitales crónicas por virus del herpes simple en paciente inmunocomprometido: reporte de caso

Baquedano-Ordoñez

Martel-Ramos

2022

Rev Hisp Cienc Salud

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Genital ulcers caused by sexually transmitted agents

Ramos¹,

Nicola²,

Bezerra³

et al. 2022

Anais Brasileiros de Dermatologia

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Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study

Bazzo,

Machado,

Martins

et al. 2024

Sex Transm Infect

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BackgroundLittle is known about the aetiology of urethral discharge syndrome (UDS) and genital ulcer disease (GUD) in Brazil due to limited access to laboratory tests and treatment based mainly on the syndromic approach.ObjectivesTo update Brazilian treatment guidelines according to the current scenario, the first nationwide aetiological study for UDS and GUD was performed.MethodsMale participants with urethral discharge (UD) and/or genital ulcer (GU) reports were enrolled. Sample collection was performed by 12 sentinel sites located in the five Brazilian regions. Between 2018 and 2020, 1141 UD and 208 GU samples were collected in a Universal Transport Medium-RT (Copan). A multiplex quantitative PCR kit (Seegene) was used to detect UD:Chlamydia trachomatis(CT),Mycoplasma genitalium(MG),M. hominis(MH),Neisseria gonorrhoeae(NG),Trichomonas vaginalis(TV),Ureaplasma parvum(UP),U. urealyticum(UU) and another kit to detect GU: cytomegalovirus (CMV),Haemophilus ducreyi(HD), herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2), lymphogranuloma venereum (LGV),Treponema pallidum(TP) and varicella-zoster virus (VZV).ResultsIn UD samples, the frequency of pathogen detection was NG: 78.38%, CT: 25.6%, MG: 8.3%, UU: 10.4%, UP: 3.5%, MH: 3.5% and TV: 0.9%. Coinfection was assessed in 30.9% of samples, with 14.3% of NG/CT coinfection. The most frequent pathogen identified in GU was HSV2, present in 40.8% of the samples, followed by TP at 24.8%, LGV and CMV at 1%, and HSV1 at 0.4%. Coinfection of TP/HSV2 was detected in 4.4% of samples. VZV and HD were not detected. In 27.7% of the GU samples, no pathogen was detected.ConclusionThis study provided the acquisition of unprecedented data on the aetiology of UDS and GUD in Brazil, demonstrated the presence of a variety of pathogens in both sample types and reaffirmed the aetiologies known to be most prevalent globally.

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Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: infecções que causam úlcera genital

Cited by 3 publications

References 29 publications

Úlceras genitales crónicas por virus del herpes simple en paciente inmunocomprometido: reporte de caso

Úlceras genitales crónicas por virus del herpes simple en paciente inmunocomprometido: reporte de caso

Genital ulcers caused by sexually transmitted agents

Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study

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