Different nutritional-state indicators of HIV-positive individuals undergoing antiretroviral therapy

Abstract

This study aimed at learning about the nutritional profile of HIV-positive individuals undergoing antiretroviral therapy and at comparing the performance of nutritional-state indicators. A transversal study was performed on 94 patients attending the Tropical Diseases Outpatient Hospital of Botucatu Medical School (FMB) - UNESP. The body mass index (BMI) and the classification by Papini-Berto (PB) were used to evaluate nutritional state, aiming at detecting malnutrition and obesity. The waist-to-hips ratio (W/HR) and waist circumference (WC) were adopted for identification of abdominal obesity and lipodystrophy. According to BMI, most of the individuals were eutrophic, followed by 30.9% overweight and 6.4% malnourished. By using the PB classification, the frequency of malnourished increased (22.3%). The analysis of the PB classification in relation to BMI indicated that the former presented high sensitivity and good specificity for malnutrition diagnosis, namely 100% and 83%, respectively. The prevalence of abdominal obesity was 7.44% according to WC, and a higher prevalence (38.3%) was observed when taking W/HR into account. There was significant positive association between nutritional diagnosis according to PB and T CD4+ lymphocyte. The results support the use of PB classification for malnutrition detection as well as that of BMI and W/HR for overweight and fat redistribution

Effects of Aqueous Extract of <em>Cyphostemma glaucophilla</em> Leaves on Some Specific and Non-specific Immune Responses in Albino Rats

“…The most prevalent cause of immunodeficiency worldwide is severe malnutrition which affects as much as 50% of the population in some impoverished communities (Geralx et al, 2008). Availability of complement component and Phagocyte function are compromised during malnutrition which will directly affect pathogen elimination.…”

Too little, too late: Comparison of nutritional status and quality of life of nutrition care and support recipient and non-recipients among HIV-positive adults in KwaZulu-Natal, South Africa

“…5-24.9 kg/m 2 ), overweight (25-30 kg/m 2 ) and obesity (>30 kg/m 2 ) [37]. Waist-hip ratio (WHR) was used to identify central obesity (>0.95 for men; >0.85 for women) [38] and MUAC for wasting (<23 cm for male; < 22 cm for female).…”

Impact of malnutrition on immunity and infection

“…Secondary or acquired immunodeficiency is the loss of immune function that results from a variety of extrinsic factors. The most well known secondary immunodeficiency is caused by the human immunodeficiency virus (HIV) infection; however, the most prevalent cause of immunodeficiency worldwide is severe malnutrition, which affects as much as 50% of the population in some impoverished communities (24). The consequent abnormalities of the immune system affect both the innate and adaptive immunity.…”