2009
DOI: 10.1590/s1676-24442009000100007
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Atualização sobre hemoglobina glicada (HbA1C) para avaliação do controle glicêmico e para o diagnóstico do diabetes: aspectos clínicos e laboratoriais

Abstract: Atualização sobre hemoglobina glicada (HbA 1C) para avaliação do controle glicêmico e para o diagnóstico do diabetes: aspectos clínicos e laboratoriais Update on glycated hemoglobin (HbA 1C) for assessment of glycemic control and the diagnosis of diabetes: clinical and laboratory aspects

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Cited by 54 publications
(35 citation statements)
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References 12 publications
(18 reference statements)
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“…14,[25][26][27] Over the years, prolonged hyperglycemia can cause extensive and irreversible organic wounds, affecting the eyes, kidney, nerves, large and small vessels, as well as blood coagulation. 33 Findings from the United Kingdom Prospective Diabetes Study (UKPDS) confirm that the ideal glycemic control in patients with DM2 reduces the development and advancement of a large number of complications resulting from the disease. 34 Differently from glycemic tests, which reflect the glycemic levels at the exact moment of measurement, the HbA1c tests indicate the average glucose levels from the last two to four months.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…14,[25][26][27] Over the years, prolonged hyperglycemia can cause extensive and irreversible organic wounds, affecting the eyes, kidney, nerves, large and small vessels, as well as blood coagulation. 33 Findings from the United Kingdom Prospective Diabetes Study (UKPDS) confirm that the ideal glycemic control in patients with DM2 reduces the development and advancement of a large number of complications resulting from the disease. 34 Differently from glycemic tests, which reflect the glycemic levels at the exact moment of measurement, the HbA1c tests indicate the average glucose levels from the last two to four months.…”
Section: Discussionmentioning
confidence: 99%
“…33 Therefore, the last two to three months need to be considered when measuring it, and this is an important recommendation when testing treatment effectiveness. 35 Taking into consideration the measurement of HbA1c levels at the end of the interventions carried out in each of the analyzed studies in the present research, eight of them 4,24-30 complied with the recommendations of the Brazilian Diabetes Society (SBD) and measured the HbA1c levels after two, 28 three to six 4,[25][26]30 and twelve months of intervention.…”
Section: Discussionmentioning
confidence: 99%
“…O termo HbA1C refere-se a união entre a hemoglobina A (HbA) e alguns açucares através de reações não-enzimática continua, lenta e irreversível definida como glicação e ocorre em maior ou menor grau, conforme o nível de glicemia (SUMITA; ANDRIOLO, 2008;NETTO et al, 2009). A quantidade de glicose ligada a hemoglobina é diretamente proporcional a concentração média de glicose no sangue e a meia vida dos eritrócitos, sendo capaz de fornecer uma avaliação do controle glicêmico médio no período de 90 a 120 dias que antecedem a coleta de sangue para o exame (CAVAGNOLLI, 2009;SBD, 2013SBD, -2014.…”
Section: Fonte: Elaborado Pelos Autoresunclassified
“…Níveis elevados de hemoglobina fetal, HbF, utilizada através do medicamento hidroxiureia para tratamento da anemia falciforme, por exemplo, pode resultar na diminuição dos níveis da HbA1c 40 . Ingestão crônica de aspirina e/ou altas doses de vitamina E e C, assim como outros antioxidantes, podem diminuir a concentração de HbA1c pois causam a inibição de glicação da hemoglobina 41 . Porém, permance incerto qual destes fenômenos é o responsável por gerar a diferente valorização da HbA1c na prática clínica 12 .…”
Section: Kidney Intunclassified