Medidas murinométricas e eficiência alimentar em ratos provenientes de ninhadas reduzidas na lactação e submetidos ou não ao exercício de natação

Abstract

Introduction: Overfeeding in early life can persistently modify consumption and body weight. Adoption of exercise is one useful strategy to prevent excessive weight gain. Objective: to assess body growth and feed efficiency in rats from reduced litters during lactation. Methods: On day 3 of life, litters were formed with 4 (GN4) or 10 animals (GN10) (n = 25). When weaned, Wistar male rats were kept in individual cages and at day 60 (± 2) they were divided into sedentary (SED) and exercised (NAT -swimming), forming thus four groups: GN4SED; GN10SED; GN4NAT and GN10NAT. Assessment consisted of weight, weight gain and specific rate of weight gain, epididymal fat, Body Mass and Lee Indices, consumption and feed efficiency, blood glucose and lactemia. Results: At day 21, GN4 had body weight 52% above GN10 (P = 0.001). However, at days 30 and 60, their weight was not different. At the end of the period, GN10NAT showed lower weight (356.82 ± 23.04) that GN10SED (409.28 ± 17.30), but GN4NAT was heavier (417.85 ± 37.91) than GN4SED (413.69 ± 57.45) and GN10NAT. GN4 presented higher rate of weight gain during lactation, but slower after weaning. Regardless of litter size, rate of weight gain reduces as age progresses. At the end of this period, blood glucose, total and relative epididymal fat, and Lee and BMI indices did not differ between groups. Pre and post-exercise lactate values are consistent with moderate effort. In periadolescence, GN4 showed lower food intake, but with no differences in adulthood. Conclusion: Reduced litter during lactation did not affect body weight or food intake persistently. However, the swimming protocol was effective in reducing weight gain in control animals, but not in animals from reduced litters.

Influence of creatine supplementation on indicators of glucose metabolism in skeletal muscle of exercised rats

“…Therefore, our hypothesis was that the observed body weight loss of the animals was not due to creatine supplementation but was solely a result of exercise. These results are in agreement with the literature reports of rats trained on treadmills using aerobic intensity protocols in which exercise reduced feed intake and, consequentially, resulted in weight loss (Bernardes et al, 2004;Silveira et al, 2008;Nery et al, 2011). Silveira et al (2008) argued that, in response to physical training, there is an increase in lean mass, a decrease in fat mass, and a high uptake of fatty acids by the exercised tissue.…”

Effects of <i>Pereskia aculeata</i> Miller on the Biochemical Profiles and Body Composition of Wistar Rats

“…The Lee index determined in this study is an anthropometric parameter used to assess over weight and obesity in rats [21], and no significant changes in this indicator were found in this study. Therefore, the types of treatment did not affect the animals' weight gain, and hence, the overweight and obesity rate, since, according to Nery et al (2011) [22], a Leeindex higher than 0.3 can be used as an evaluator of overweight. The accumulation of visceral fat may be the best predictor of cardiovascular disease, because, according Vasquez et al (2010) [23], visceral fat has adeleterious effect on the metabolic and hemodynamic parameters and is linked to insulin resistance, glucose intolerance, arterial hypertension, and dyslipidemias.…”

Suplementação Com Amêndoa De Bacuri Na Composição Corporal De Ratos Submetidos Ao Exercício

“…Porém, no presente estudo, todos os grupos iniciaram o protocolo de treinamento e suplementação proteica com valores próximos a 0,6 aumentando para 0,8. Para Angéloco et al 28 , o IMC pode estimar de forma confiável a gordura corporal em rato, sendo diretamente proporcional ao seu crescimento, já o índice de Lee é considerado menos sensível, pois animais com elevada quantidade de massa muscular podem apresentar elevado índice de Lee mesmo que a gordura corporal não seja excessiva [19][20][21] .…”

“…Entretanto, o índice de Lee e o IMC foram superiores no bacuri sedentário em relação ao controle exercitado, os dois índices são determinantes de massa muscular e preditores de excesso de peso 21 .…”