First isolation of leptospires from dairy goats in Brazil

Lilenbaum, Walter; Morais, Zenáide Maria de; Gonçales, Amane Paldês; Souza, Gisele Oliveira de; Richtzenhain, Leonardo José; Vasconcellos, Sílvio Arruda

doi:10.1590/s1517-83822007000300023

Cited by 23 publications

(20 citation statements)

References 8 publications

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“…Lilenbaum et al (2007a) cultivaram amostras de urina de caprinos clinicamente saudáveis, originários de rebanhos localizados no estado do Rio de Janeiro, e efetuaram o primeiro isolamento de leptospiras em caprinos do pais.…”

Section: Isolamentos De Leptospira Spp Em Ovinos E Caprinos No Brasilunclassified

Leptospirose em pequenos ruminantes: situação epidemiológica atual no Brasil

Higino

Azevêdo

2014

Arq. Inst. Biol.

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Leptospirosis in small ruminants is a disease that can lead to economic losses due to the occurrence of abortions, stillbirths and decreased milk production. The infection can be presented in acute, chronic and inapparent forms. In the acute infection, anorexia, depression, difficulty breathing, fever, hemoglobinemia and hemoglobinuria can occur. In the chronic form, abortions and stillbirths are common. Several recent serological surveys conducted in Brazil revealed frequencies of seropositivity ranging from 3.4 to 31.3% in goats, and from 0.7 to 34.6% in sheep. Most frequent reactions were obtained with the serovars Autumnalis, Grippotyphosa, Hardjo, Icterohaemorrhagiae and Pyrogenes. The microscopic agglutination test is the most used method to diagnose the infection. The control of leptospirosis in small ruminants is based on the identification of sources of infection, rodent control, control in animal purchasing and systematic immunization with inactivated vaccines that contain regional serovars of leptospires.KEYWORDS: Leptospira spp.; small ruminants; epidemiology; control; prevention. RESumO:A leptospirose em pequenos ruminantes é uma doença que pode causar perdas econômicas devido à ocorrência de abortamentos, natimortalidade e diminuição da produção de leite. A infecção pode se apresentar nas formas aguda, crônica e inaparente. Na forma aguda, pode ocorrer anorexia, depressão, dificuldade respiratória, febre, hemoglobinemia e hemoglobinúria. Na forma crônica, abortamentos e natimortalidade são comuns. Vários inqué-ritos sorológicos recentes conduzidos no Brasil apontaram frequências de soropositividade variando de 3,4 a 31,3% em caprinos, e de 0,7 a 34,6% em ovinos. Os sorovares reatores mais frequentes foram Autumnalis, Grippotyphosa, Hardjo, Icterohaemorrhagiae e Pyrogenes. O teste de soroaglutinação microscópica é o método mais empregado para o diagnóstico da infecção. O controle da leptospirose em pequenos ruminantes é baseado na identificação de fontes de infecção, controle de roedores, controle da aquisição de animais e imunização sistemática com vacinas inativadas que contenham sorovares de leptospiras regionais.Palavras-chave: Leptospira spp.; pequenos ruminantes; epidemiologia; controle; prevenção.

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Section: Isolamentos De Leptospira Spp Em Ovinos E Caprinos No Brasilunclassified

Leptospirose em pequenos ruminantes: situação epidemiológica atual no Brasil

Higino

Azevêdo

2014

Arq. Inst. Biol.

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“…In Brazil, leptospirosis has been scarcely reported for sheep concerning its etiology and spirochete isolation (Lilenbaum et al 2007(Lilenbaum et al , 2008. Thus, the present study aimed to determine the frequency of Leptospira spp.…”

Section: Introductionmentioning

confidence: 97%

Frequency of Leptospira spp. in sheep from Brazilian slaughterhouses and its association with epidemiological variables

et al. 2012

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Leptospirosis is a worldwide anthropozoonosis that infects livestock, including sheep as the carriers to other animals and humans. The present study aimed to determine the prevalence of Leptospira spp. in sheep from two slaughterhouses in the state of São Paulo, Brazil and its association with epidemiological variables. Serum samples from 182 sheep were evaluated for Leptospira spp. antibodies by microscopic agglutination test (MAT). Results indicated 34/182 (18.68%; CI95% 13.70-24.98%) positive serum samples, mainly to the serovar Copenhageni (17/34; 50%; CI95% 33.99-66.01%). Bacterial growth in the Fletcher medium was detected for 13/34 (38.24%; CI95% 23.87-55.08%) animals, and confirmed by Polymerase Chain Reaction (PCR) and sequencing for only two kidney samples from two animals. Thus, treatment and vaccination of sheep, besides rodent control, can be useful to prevent the infection in the studied region since sheep are important Leptospira spp. carriers, and its transmission to slaughterhouse workers is mainly through the manipulation of visceral tissues.

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“…The only serogroup isolated from goats in Brazil is Grippotyphosa, which has been reported in cultivated urine samples (LILENBAUM et al, 2007a). Studies involving goat herds from Brazilian states reported the following risk factors associated with the occurrence of Leptospira spp.…”

Section: Introductionmentioning

confidence: 99%

Frequency of and risk factors associated to Leptospira spp. Seropositivity in goats in the state of Sergipe, Northeastern Brazil

et al. 2017

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Frequency of and risk factors associated to Leptospira spp. seropositivity in goats in the state of Sergipe, Northeastern... Ciência Rural, v.47, n.7, 2017. INTRODUCTIONLeptospirosis is a major public health problem in Brazil with an annual average rate of 3,780 human cases between 2000 and 2015, 9.6% (364) of which were lethal. In the country's Northeastern region and in the state of Sergipe, lethality is as high as 12.8% (87/681) and 24.1% (10.6/44), respectively (SINAN/SVS/MS, 2017a, b). Leptospirosis is caused by spirochetes of the genus Leptospira. Twenty-five serogroups and approximately 300 serovars belonging to 25 serogroups can infect domestic animals, wildlife, and humans. On rural properties, transmission occurs primarily via the urine of infected animals (GOMES, 2013;HIGINO & AZEVEDO, 2014). Accordingly, rural workers in Jamaica who have contact with goats have a 3.52 times higher chance of presenting symptoms of the disease (KEENAN et al., 2010).Goats usually present chronic infection, with a predominance of embryonic absorption, miscarriage, neonatal mortality, and hemorrhagic jaundice. In the acute form of the disease, a sudden onset of fever, anemia, jaundice, and hemoglobinuria occur, leading to death (MARTINS et al., 2012;HIGINO & AZEVEDO, 2014).In the Northeastern region of Brazil, surveys were performed in the states of Rio Grande do Norte, Ceará, Paraíba, and Pernambuco. The rate of seropositive goats based on the microscopic

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First isolation of leptospires from dairy goats in Brazil

Cited by 23 publications

References 8 publications

Leptospirose em pequenos ruminantes: situação epidemiológica atual no Brasil

Leptospirose em pequenos ruminantes: situação epidemiológica atual no Brasil

Frequency of Leptospira spp. in sheep from Brazilian slaughterhouses and its association with epidemiological variables

Frequency of and risk factors associated to Leptospira spp. Seropositivity in goats in the state of Sergipe, Northeastern Brazil

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