Anti-Candida activity and chemical composition of Cinnamomum zeylanicum blume essential oil

Lima, Edeltrudes O.

doi:10.1590/s1516-89132013000500005

Cited by 22 publications

(37 citation statements)

References 27 publications

(26 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…12 Our study also show cinnamon oil as most effective in other isolated yeast species also similar to the study published in Brazilian archives of Biology and technology which also noted that cinnamon oil inhibits all the strains of C. albicans, C. tropicalis and C. krusei. 21 Clove oil showed high activity against all isolates of yeast species which is similar to study conducted by Amit kumar et al and Hammer et al which showed significant antifungal activity of clove oil against candida species isolated from blood stream infections. 22,23 Carvacrol found in clove oil is able to kill C.albicans by producing lesions in plasma membrane causing organism death.…”

Section: Discussionsupporting

confidence: 86%

Antifungal activity of various plant oils against yeast isolates from ICU patients

Suman¹,

Chauhan²,

Lata³

et al. 2017

Int J Res Med Sci

View full text Add to dashboard Cite

Background: To evaluate the in-vitro antifungal activity of various essential plant oils against yeast species.Methods: The present study was a prospective study conducted in Department of Microbiology along with Department of Pharmacology at Tertiary care teaching hospital. Various clinical samples from ICU patients were inoculated on Sabourauds Dextrose Agar (SDA) in accordance with the standard methods. Yeast isolates were recovered and identified as per standard recommended procedure. The antifungal activity of plant oils against these isolated yeasts was determined using disc diffusion method. The results were interpreted as <9mm-inactive, 9-12mm-partially active, 13-18mm-very active. Fluconazole and Itraconazole were taken as control drugs.Results: The various yeast isolated were C. albicans, C. tropicals, C. krusei, C. glabrata, C. gulliermondi, C. keyfr, Cryptococcus and Tricosporon. Among essential plant oils, Cinnamon oil and clove oil showed high activity against all isolated yeast species. Olive oil showed least antifungal activity. Fluconazole was resistant in all yeast isolates, while Itraconazole was sensitive to all yeast isolates. Sensitivity of cinnamon and clove oil was statistically significant than Itraconazole.Conclusions: To conclude present study shows the potential of essential plant oils as newer therapeutic alternatives to antifungal drugs. These may be used in combination with antifungal agents to overcome drug resistance, adverse effects and in shortening the long-term treatment with antifungal drugs. Thus, these essential plant oils can be used in future as antifungal agents in azoles resistant strains.

show abstract

Section: Discussionsupporting

confidence: 86%

Antifungal activity of various plant oils against yeast isolates from ICU patients

Suman¹,

Chauhan²,

Lata³

et al. 2017

Int J Res Med Sci

View full text Add to dashboard Cite

show abstract

“…Experimental in vitro and in vivo studies in animals and humans, conducted in different regions of the world, have shown numerous beneficial effects of C. zeylanicum on health [ 16 ]. Its analgesic, antiseptic, antispasmodic, astringent, insecticidal, and antimicrobial properties are among the main indications for its use [ 17 – 20 ]. These studies are linked to the idea of the low toxicity of extracts obtained from this plant, considering that it is used as food by human populations and that previous investigations in animals indicated no significant toxic effects, with wide therapeutic potential [ 16 , 21 ], with reported hepatoprotective [ 22 ] and antioxidant effects [ 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Safety and Tolerability of Essential Oil fromCinnamomum zeylanicumBlume Leaves with Action on Oral Candidosis and Its Effect on the Physical Properties of the Acrylic Resin

Oliveira

Silva

Trindade

et al. 2014

Evidence-Based Complementary and Alternative Medicine

Self Cite

View full text Add to dashboard Cite

The anti-Candida activity of essential oil from Cinnamomum zeylanicum Blume, as well as its effect on the roughness and hardness of the acrylic resin used in dental prostheses, was assessed. The safety and tolerability of the test product were assessed through a phase I clinical trial involving users of removable dentures. Minimum inhibitory concentration (MIC) and minimum fungicidal concentrations (MFC) were determined against twelve Candida strains. Acrylic resin specimens were exposed to artificial saliva (GI), C. zeylanicum (GII), and nystatin (GIII) for 15 days. Data were submitted to ANOVA and Tukey posttest (α = 5%). For the phase I clinical trial, 15 healthy patients used solution of C. zeylanicum at MIC (15 days, 3 times a day) and were submitted to clinical and mycological examinations. C. zeylanicum showed anti-Candida activity, with MIC = 625.0 µg/mL being equivalent to MFC. Nystatin caused greater increase in roughness and decreased the hardness of the material (P < 0.0001), with no significant differences between GI and GII. As regards the clinical trial, no adverse clinical signs were observed after intervention. The substance tested had a satisfactory level of safety and tolerability, supporting new advances involving the clinical use of essential oil from C. zeylanicum.

show abstract

“…e MBC of the test substances and of the positive control was determined from the MIC result. For this purpose, 10 μl of the corresponding inhibitory concentration and the immediately higher concentrations (MIC × 2 and MIC × 4) [18] were subcultured on Petri dishes containing BHI agar. After 24 h of incubation under anaerobic conditions, the MBC was determined using the ImageJ software and was defined as the lowest concentration that inhibited visible growth of the subculture [16].…”

Section: Mcfarland Standard) a 96-well Flat-bottom Plate (Costar ® )mentioning

confidence: 99%

Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis

Silva

Alves

Silva

et al. 2019

BioMed Research International

View full text Add to dashboard Cite

is study aimed to evaluate the efficacy of different concentrations of essential oils combined with calcium hydroxide against Enterococcus faecalis. irteen experimental groups were formed: NC (negative control); PC (positive control); GC (growth control); SC (sterilization control); RO (Rosmarinus officinalis); ROH (calcium hydroxide + RO); ZO (Zingiber officinale); ZOH (calcium hydroxide + ZO); AB (Citrus aurantium bergamia); ABH (calcium hydroxide + AB); CO (Copaifera officinalis); COH (calcium hydroxide + CO); DWH (calcium hydroxide and distilled water). After reconstitution of the E. faecalis strain, microdilution testing was performed to define the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). e data were tabulated in an Excel spreadsheet, and the MIC and MBC were calculated in accordance with the Bacteriological Analytical Handbook. MICs in the range of 0 to 100 mg/ml were only observed in the ROH group. e RO, ROH, AB, ZO, and ZOH presented absolute data for MBC. Bacterial growth was detected in the DWH group at all concentrations tested. e combination of the essential oils tested here with calcium hydroxide appears promising as an intracanal medication in endodontic treatment because of its effectiveness against Enterococcus faecalis. Essential oils are important in endodontic therapy since calcium hydroxide, the gold standard intracanal medication, is not effective against E. faecalis.

show abstract

Anti-Candida activity and chemical composition of Cinnamomum zeylanicum blume essential oil

Cited by 22 publications

References 27 publications

Antifungal activity of various plant oils against yeast isolates from ICU patients

Antifungal activity of various plant oils against yeast isolates from ICU patients

Safety and Tolerability of Essential Oil fromCinnamomum zeylanicumBlume Leaves with Action on Oral Candidosis and Its Effect on the Physical Properties of the Acrylic Resin

Antibacterial Activity of Rosmarinus officinalis, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis Alone and in Combination with Calcium Hydroxide against Enterococcus faecalis

Contact Info

Product

Resources

About