Diverse microorganisms inhabit the oral cavity, of which many are involved in the beginning and progression of dental caries and other pathologies at an oral level. Among these, the family of the genus Streptococcus is the most relevant in the process of dental caries. On the other hand, Enterococcus faecalis is especially frequent in infections of dental origin, being considered one of the main pathogens in dentistry. [1] These microorganisms are usually complex microorganisms and have not yet been fully investigated. The oral cavity is characterized by containing different structures in which microorganisms can replicate. Each part in the mouth contains a specific characteristic biofilm, involving many different bacterial species which interact dynamically leading to changes in the flora of the oral cavity and in the life of the host. [1][2][3] The prolonged use of antimicrobials and antiseptics can lead to adverse reactions at the oral level, such as pigmentation of the teeth and alterations of taste, and, therefore, new treatment alternatives without adverse effects and that are adjuvants to tooth brushing are being investigated for the treatment of bacterial plaque removal. [3][4][5][6] In the area of phytotherapy, plants such as rosemary are rich in active principles and have multiple actions on the human organism. Rosemary is grown in our country and in the last decade, studies on the properties of this plant have been developed in order to provide information on its therapeutic potential, [7][8][9] Rosmarinus officinalis has some applications in