Acetylsalicylic acid and labeling of blood constituents with technetium-99m

Fonseca, Adenilson de Souza da; Frydman, Jacques Natan Grinapel; Rocha, Vinícius Novaes; Bernardo-Filho, Mário

doi:10.1590/s1516-89132005000700024

Cited by 4 publications

(2 citation statements)

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“…Technetium-99m ( 99m Tc), as sodium pertechnetate (Na 99m TcO 4 ), is the most widely used radionuclide in diagnostic nuclear medicine procedures in Single Photon Emission Computed Tomography (SPECT) examinations 21 . 99m Tc-radiopharmaceutical has also been used in studies to evaluate the effects of drugs 22 and plant extracts 23 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2014

IJPSR

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Authors have reported that these exercises can increase the leg muscle force, power, rate of force development and movement velocity 1, 2 . Moreover, provide significant improvements in the functional capacity in severe chronic obstructive pulmonary disease 3 . Significant increase in bone mineral density has been also reported 4 .Vibrations can be defined as an oscillatory motion. They can be generated in oscillating/vibratory platforms and transmitted, in general, by the feet to the whole body of a person 3 .

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Section: Introductionmentioning

confidence: 99%

Untitled

2014

IJPSR

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“…(2001) have reported studies with Escherichia coli cultures evaluating the influence of crude extracts on the survival of the strain submitted to SnCl 2 . Fonseca et al. (2005) have described evaluation of the effect of Acetylsalicylic acid on the labeling of blood constituents with 99mTc.…”

Section: Introductionmentioning

confidence: 99%

The male reproductive system and the effect of an extract of a medicinal plant (Hypericum perforatum) on the labeling process of blood constituents with technetium-99m

Santos-Filho

Fonseca

Bernardo-Filho

2007

Braz. arch. biol. technol.

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Hypericum perforatum (hiperico) is a plant that has been used to treat diseases and also inhibits rat and human vas deferens contractility. In nuclear medicine, stannous chloride (SnCl2) is used as a reducing agent to obtain radiopharmaceuticals labeling with technetium-99m. As the SnCl2 seems to have adverse effects related with the reproductive performance of male rabbits as well as the human consumption of hiperico might affect sexual function. In the present work, consistent results show significant changes on the blood constituents labeled by technetium-99m obtained from young rats under the effect of an hiperico extract as opposed to blood samples equally treated taken from elderly rat.. Supposedly, this extract could protect the male reproductive system against action of SnCl2 at least in young rats. The findings described in this work allow introducing a simple assay to evaluate the action of products that could interfere with the male reproductive system.
Hypericum perforatum (hiperico) tem sido utilizado para tratar diferentes distúrbios e também inibir a contractilidade do ducto deferente em ratos e em humanos. Na medicina nuclear, o cloreto estanoso (SnCl2) é usado como um agente redutor para obter radiofármacos marcados com tecnécio-99m. Como o SnCl2 parece acarretar efeitos indesejáveis relacionados com o desempenho reprodutivo de coelhos machos e o hiperico pode afetar a função sexual em humanos, o objetivo desse trabalho é apresentar resultados sobre o efeito de um extrato de hiperico na marcação de constituintes sangüíneos com o tecnécio-99m retirados de ratos jovens e idosos. O hiperico parece alterar a marcação de constituintes sangüíneos com tecnécio-99m isolados de sangue de animais jovens. Embora, esse resultado não seja observado em ratos idosos. Provavelmente, o extrato poderia apresentar uma ação protetora para o sistema reprodutivo contra a ação do SnCl2, pelo menos em ratos jovens. Os resultados descritos nesse trabalho permitem introduzir um ensaio simples para avaliar a ação de produtos que poderiam interferir com o sistema reprodutor masculino

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