Behaviorial inhibition and history of childhood anxiety disorders in Brazilian adult patients with panic disorder and social anxiety disorder

Isolan, Luciano; Zeni, Cristian Patrick; Mezzomo, Kélin Maggioni; Blaya, Carolina; Kipper, Letícia; Heldt, Elizeth Paz da Silva; Manfro, Gisele Gus

doi:10.1590/s1516-44462005000200005

Cited by 11 publications

(5 citation statements)

References 27 publications

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“…Reportedly, behavioral inhibition is a possible precursor for anxiety disorder, especially SAD (Hayward et al, 1998). SAD has shown especially high scores on school/social behavioral inhibition compared with panic and other anxiety disorders (Isolan et al, 2005). Our results show that the experience of behavioral inhibition does not differ between the social/school and fear/illness subscales.…”

Section: Discussionmentioning

confidence: 49%

Comparison of Anxiety-Related Traits Between Generalized and Nongeneralized Subtypes of Social Anxiety Disorder

Lim

Shin

et al. 2011

Journal of Nervous &Amp; Mental Disease

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This study aimed to investigate the possible difference in anxiety-related traits between the generalized and nongeneralized subtypes of social anxiety disorder (SAD). Two hundred seventy-three SAD Korean outpatients completed the Anxiety Sensitivity Index (ASI), the Trait Form of the State-Trait Anxiety Inventory (STAI-T), Retrospective Self-Report of Inhibition (RSRI), and the Liebowitz Social Anxiety Scale (LSAS) as part of their assessments. The unadjusted total scores of the ASI, STAI-T, RSRI, and LSAS differed between the two subtypes, according to an independent t-test. However, this result was not significant (ASI: F = 2.363, p = 0.127; STAI-T: F = 0.004, p = 0.949; RSRI: F = 1.518, p = 0.220) after adjusting for LSAS total score. The comparison of anxiety-related traits did not show any difference between the subtypes after adjusting for illness severity. These results may suggest that the two SAD subtypes are on a continuum of the same illness, differentiated only by symptom severity.

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Section: Discussionmentioning

confidence: 49%

Comparison of Anxiety-Related Traits Between Generalized and Nongeneralized Subtypes of Social Anxiety Disorder

Lim

Shin

et al. 2011

Journal of Nervous &Amp; Mental Disease

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“…Another interesting piece of evidence implicating CRF in anxiety disorders is demonstrated by the association of a single nucleotide polymorphism in the CRF gene with behavioral inhibition (Smoller et al, 2005); a heritable tempermental phenotype in children evidenced by fearful, avoidant or shy behaviour in novel situations. Behavioural inhibition is a risk factor for the development of panic disorder and social phobia (Isolan et al, 2005).…”

Section: Depression and The Hpa Axismentioning

confidence: 99%

Modulation of stress by imidazoline binding sites: Implications for psychiatric disorders

Smith

Jessop

Finn

2009

Stress

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In this review, we present evidence for the involvement of imidazoline binding sites (IBS) in modulating responses to stress, through central control of monoaminergic and hypothalamo-pituitary-adrenal (HPA) axis activity. Pharmacological and physiological evidence is presented for differential effects of different IBS subtypes on serotoninergic and catecholaminergic pathways involved in control of basal and stress-stimulated HPA axis activity. IBS ligands can modulate behavioural and neuroendocrine responses in animal models of stress, depression and anxiety, and a body of evidence exists for alterations in central IBS expression in psychiatric patients, which can be normalised partially or fully by treatment with antidepressants. Dysfunction in monoaminergic systems and the HPA axis under basal and stress-induced activation has been extensively reported in psychiatric illnesses. On the basis of the literature, we suggest a potential therapeutic role for selective IBS ligands in the treatment of depression and anxiety disorders.

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“…The aims of this study were to investigate differences in anxiety‐related traits and clinical characteristics between early‐ and late‐onset SAD among Korean clinical populations. Previous researchers have consistently shown that a hereditary temperamental trait of behavioural inhibition is commonly an antecedent to the development of SAD 15,16 . The aim of this study was to elucidate the clinical differences between early‐ and late‐onset SAD in the Korean population.…”

Section: Introductionmentioning

confidence: 97%

“…Previous researchers have consistently shown that a hereditary temperamental trait of behavioural inhibition is commonly an antecedent to the development of SAD. 15,16 The aim of this study was to elucidate the clinical differences between early-and late-onset SAD in the Korean population.…”

Section: Introductionmentioning

confidence: 99%

Clinical differences between early‐ and late‐onset social anxiety disorders

Lim

Shin

et al. 2012

Early Intervention Psych

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Behaviorial inhibition and history of childhood anxiety disorders in Brazilian adult patients with panic disorder and social anxiety disorder

Abstract: Our data are in accordance to the literature and corroborates the theory of an anxiety diathesis, suggesting that a history of anxiety disorders in childhood is associated with an anxiety disorder diagnosis, mainly social anxiety disorder, in adulthood.

Cited by 11 publications

References 27 publications

Comparison of Anxiety-Related Traits Between Generalized and Nongeneralized Subtypes of Social Anxiety Disorder

Comparison of Anxiety-Related Traits Between Generalized and Nongeneralized Subtypes of Social Anxiety Disorder

Modulation of stress by imidazoline binding sites: Implications for psychiatric disorders

Clinical differences between early‐ and late‐onset social anxiety disorders

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