Uso da capilaroscopia ungueal como método diagnóstico e prognóstico de rosácea

Fonseca, Gabriela Poglia; Brenner, Fabiane Mullinari; Müller, Carolina de Souza; Wojcik, Adma Lima

doi:10.1590/s0365-05962011000100011

Cited by 12 publications

(9 citation statements)

References 11 publications

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“…While systemic sclerosis and Raynaud’s phenomenon are the two most common diseases for which NFC is performed in determining the diagnosis and prognosis [ 8 ], changes in the nailfold capillaries have been identified in several conditions, including autoimmune diseases, rheumatic diseases [ 9 ], peripheral arterial obliterative disorders [ 10 ], venous insufficiency [ 11 ], diabetes mellitus [ 12 ], hypertension [ 13 ], psoriasis [ 14 ], and aging [ 15 ]. In a recent study, NFC was performed in rosacea patients, but no specific findings were revealed [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of demodicosis, nailfold capillaroscopy, and oxidative stress in rosacea: a case-control study

Karabay

Demirel

2021

pdia

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Introduction Inflammation, immune system disorders, Demodex infestation, neurovascular dysregulation and oxidative stress are thought to be contributory factors in the pathogenesis of rosacea. Aim To evaluate the presence of Demodex mites, the morphologic features of the nailfold capillaries, and the systemic oxidative stress status in patients with rosacea. Material and methods Thirty-one patients diagnosed with rosacea and 37 healthy age- and gender-matched subjects were included in this prospective case-control study. The presence of Demodex infestation, the findings of nailfold capillaroscopy (NFC), and the status of systemic oxidative stress measured by total oxidant capacity (TOC), total antioxidant capacity (TAC) and oxidative stress index (OSI) were evaluated. Results Demodex infestation rates were significantly higher in rosacea patients than in controls ( p = 0.001). Increases in the diameters of the capillaries and the presence of avascular areas and crossing and abnormal structures were significantly more common in rosacea patients than in the healthy controls ( p < 0.01, p = 0.016, p = 0.02, p < 0.001, respectively), and hairpin structures were significantly less common in rosacea patients than in the controls ( p < 0.001). The presence of crossing capillaries was positively correlated with higher TOC levels ( p = 0.05), while abnormal structures were found to be correlated with lower levels of TAC ( p = 0.045). Conclusions Oxidative status and NFC may play diagnostic and prognostic roles in rosacea, which should be confirmed by studies with larger sample sizes.

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Section: Introductionmentioning

confidence: 99%

Evaluation of demodicosis, nailfold capillaroscopy, and oxidative stress in rosacea: a case-control study

Karabay

Demirel

2021

pdia

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“…[1][2][3] Its course is irregular, with periods of flares and remission. [4][5][6] Rosacea often remains undiagnosed and inadequately managed. [7][8][9][10][11] Patients frequently report, facial flushes skin burning, itching, stinging/tingling and often feel embarrassed, thereby adding psychosocial burden to the visible clinical picture.…”

Section: Introductionmentioning

confidence: 99%

<p>A Split-Face Study Assessing the Clinical Benefit, Tolerability and Subject Satisfaction of a Dermocosmetic in Subjects with Rosacea Associated with Erythema and Sensitive Skin</p>

Berardesca¹,

Bonfigli²,

Cribier³

et al. 2020

CCID

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This study assessed the efficacy and tolerability of M89 in patients with rosacea associated with erythema and sensitive skin. Methods: Intra-individual study in a split-face design comparing after 30 days M89 twice daily and usual skin care in 20 adult subjects with rosacea and sensitive skin. M89 contains 89% Vichy volcanic mineralizing water (VVMW) and 0.4% hyaluronic acid. It is hypoallergenic and contains no perfume and this convenes in rosacea. Contained minerals reinforce the natural defences of the skin in restoring the natural skin barrier, stimulating antioxidant activity and reducing inflammation, commonly observed in subjects with rosacea. Clinical evaluations included assessment of erythema, desquamation, papules and pustules, skin tightness, dryness, burning sensation, itching, stinging and stinging test as well as local tolerability. Instrumental evaluations included skin hydration and TEWL. Subject satisfaction was assessed at Days 15 and 30. Demodex density was assessed at Day 30. Results: A significant superiority of M89 over the standard skin care was observed for erythema, skin tightness and dryness (all P≤0.05) as early as Day 15, the skin stinging test was significantly in favour of M89 (P<0.05 at Day 15 and P<0.01 at Day 30) and for skin hydration (P<0.0001) at Day 15 and 30 with no difference in mean Demodex density between M89 and usual skin care after 30 days. Tolerance was excellent and subject satisfaction very high. Conclusion: Study results concerning M89 are encouraging for its use either alone or as an adjuvant daily skin care to topical medication in patients with persistent centrofacial erythema of rosacea with no more than 3 papules and pustules.

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“…De acordo com a primeira classificação citada, a rosácea pode ser divida em estádio I -vascular, II e III -inflamatórias, e variantesfimas, oftálmica, granulomatosa, edematosa persistente, conglobata e fulminans. Já a segunda classificação, divide a rosácea em subtipo 1 (eritêmatoteleangiectásica), 2 (papulo-pustulosa), 3 (fimatosa), 4 (ocular), além de variante única (granulomatosa) 22 . O médico pode desempenhar um papel importante no aconselhamento do paciente, como reconhecer e evitar o desencadeamento do gatilho da doença.…”

Section: Discussionunclassified

Análise da qualidade de vida de pacientes portadores de dermatoses benignas em um hospital de ensino de Minas Gerais

Inácio¹,

Ottoboni²,

Paula³

et al. 2020

Rev Cienc Saude

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Objetivo: Analisar a qualidade de vida (QV) de pacientes portadores de dermatoses benignas em ambulatório de dermatologia de hospital de ensino do Sul de Minas Gerais. Métodos: Estudo quantitativo, transversal, do tipo pesquisa de campo e de perfil populacional e formas de promoção de saúde, no qual se fez a análise da QV de pacientes portadores de dermatoses benignas (psoríase, vitiligo, melasma, acne, dermatite e rosácea), de fevereiro a julho de 2017. Foram aplicados o Questionário Genérico de Qualidade de Vida - SF36 e o Dermatology Life Quality Index (DLQI-BRA), traduzidos e validados para a língua portuguesa. Resultados: Foram entrevistados 68 pacientes, dos quais 47 eram do sexo feminino (mín. 13; máx. 75 anos). No SF36, os domínios Limitação por Aspectos Emocionais (escore médio, EM, de 57,3) e Vitalidade (EM 58) foram os de pior resultado. No DLQI-BRA, o EM foi de 6,97, sendo Sintomas e Sentimentos (EM 2,69) e Atividades Diárias (EM 1,79) os de maior prejuízo para o doente. Não foram observadas correlações relevantes entre os diferentes domínios de cada questionário. Conclusão: Este estudo identificou piores escores nos Aspectos Emocionais e na Vitalidade do paciente no que diz respeito à QV de forma geral. Em relação à situação dermatológica foi pontuado escore geral de moderado efeito na QV dos pacientes. Os sintomas, sentimentos e as atividades diárias foram os fatores que causam maior prejuízo para o doente.

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Uso da capilaroscopia ungueal como método diagnóstico e prognóstico de rosácea

Abstract: Nailfold capillaroscopy presents a nonspecific pattern and does not seem to help in the diagnosis or prognosis of rosacea.

Cited by 12 publications

References 11 publications

Evaluation of demodicosis, nailfold capillaroscopy, and oxidative stress in rosacea: a case-control study

Evaluation of demodicosis, nailfold capillaroscopy, and oxidative stress in rosacea: a case-control study

<p>A Split-Face Study Assessing the Clinical Benefit, Tolerability and Subject Satisfaction of a Dermocosmetic in Subjects with Rosacea Associated with Erythema and Sensitive Skin</p>

Análise da qualidade de vida de pacientes portadores de dermatoses benignas em um hospital de ensino de Minas Gerais

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