Identificação dos insulinomas pela ecoendoscopia

Ardengh, José Celso; Valiati, Loana Heuko; Geocze, Stephan

doi:10.1590/s0104-42302004000200033

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…Several imaging modalities are available in detection and localization of NPTs, including octreotide scintigraphy or SRS (7,13,19,27,38) using radiolabeled octreotide, 111 In-DTPA-D-Phe octreotide, which binds with high affinity to somatostatin receptors (sst), transabdominal ultrasound (US), EUS (1,3,4,9,12,13,25,28,(36)(37)(38), CT (1-4, 6-9, 11, 13, 15, 16, 24, 25, 27, 31, 33, 35-38), and magnetic resonance imaging (MRI) (2,5,20,23,24,(29)(30)(31)34 In some cases, stimulated arteriography and percutaneous transhepatic venous sampling is still necessary when no other imaging study can locate a hormone-secreting tumor, but these methods are invasive (17,22).…”

Section: Discussionmentioning

confidence: 99%

Multidetector computed tomography and neuroendocrine pancreaticoduodenal tumors

et al. 2006

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Section: Discussionmentioning

confidence: 99%

Multidetector computed tomography and neuroendocrine pancreaticoduodenal tumors

et al. 2006

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64-jährige Patientin mit rezidivierenden Hypoglykämien

et al. 2007

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Insulinomas are the most common pancreatic islet cell tumours and are characterised by uncontrolled insulin secretion even in the presence of hypoglycaemia. Diagnosis is usually made by the detection of endogenous hyperinsulinism over a period of fasting. We report the case of a patient with insulinoma without hyperinsulinaemia. A secretion and overexpression of split insulin has to be discussed. The diagnosis was made by endoscopic ultrasound-guided fine-needle aspiration and the immunohistochemical detection of chromogranine. In conclusion, the present report demonstrates that insulinomas should be considered and searched for in every case of hypoglycaemia, even when associated with normal insulin levels. It also confirms the essential role of endoscopic ultrasonography in the diagnosis of insulin-secreting tumors.

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