Basic sciences and nursing

Cárnio, Evelin Capellari

doi:10.1590/s0104-11692011000500001

Cited by 5 publications

(7 citation statements)

References 1 publication

(1 reference statement)

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“…Thus, it is clear not just that these initial semesters are predominantly concerned with transmitting academic content to the students until graduation and producing good conceptual work, but that this lack of contact with reality does not allow students to understand the importance of this process (Silva, Caparroz, & Almeida, 2011). Professors involved in these students' education should engage in challenging problems and contact with other researchers, with a mind open to receiving and processing new information, so as to improve teaching quality (Carnio, 2011).…”

Section: Discussionmentioning

confidence: 99%

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Basic Cycle in Dentistry Students’ Training: The Gap in the Integration of Knowledge and Social Reality

Noro

Santos

Sette‐de‐Souza

et al. 2018

REDIE

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One of the main premises of the Dentistry curricular guidelines is the integration of knowledge, bringing together the basic, clinical and public health areas. The aim of this research was to understand how the contents of the ‚basic cycle‛ contribute to dentists' academic training. A qualitative study was performed, and developed through interviews of focal groups consisting of students from 2nd to 4th semester. The analysis produced five categories: decontextualization of social sciences, curricular structure, the gap between the basic and professional cycles, student resignation to the ‚basic cycle‛, and teachers at the core of the process. It was concluded that the dichotomy between the basic and professional cycles complicates curricular integration and compromises students' commitment to their graduation. As a result, it is necessary to incorporate the principles provided in the Dentistry curricular guidelines, such as students' proactive behavior towards the learning process and the teacher's role as a facilitator.

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Section: Discussionmentioning

confidence: 99%

“…What remained intact however, in most institutions, were the subjects in the basic cycle, which supports a range of professional education opportunities in different knowledge areas (Carnio, 2011). The basic sciences area is usually offered by different departments or centers working as isolated disciplines with their own specific content.…”

Section: Introductionmentioning

confidence: 99%

Basic Cycle in Dentistry Students’ Training: The Gap in the Integration of Knowledge and Social Reality

Noro

Santos

Sette‐de‐Souza

et al. 2018

REDIE

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“…In other words, its results applied to nursing practice can determine care activities that are supported by the pharmacological knowledge of PmB and the pathophysiology of toxic AKI, characterizing the transposition of basic experimental research to healthcare practice (13) . The second pillar -bedside -encompasses studies that evaluate the effectiveness, acceptability and cost/benefit of interventions of clinical sciences (11)(12) , exemplified by randomized studies that evaluate the effectiveness of preventive measures undertaken in patients who have risk factors for AKI during the administration of nephrotoxic drugs (14)(15) .…”

Section: Discussionmentioning

confidence: 99%

“…The second pillar -bedside -encompasses studies that evaluate the effectiveness, acceptability and cost/benefit of interventions of clinical sciences (11)(12) , exemplified by randomized studies that evaluate the effectiveness of preventive measures undertaken in patients who have risk factors for AKI during the administration of nephrotoxic drugs (14)(15) . And the last pillar -back again -adds the necessary information to convert treatments and prevention strategies in foundation for evidence-based health policies (11,13) .…”

Section: Discussionmentioning

confidence: 99%

Nephrotoxicity Of Polymyxin B: Experimental Study In Cells And Implications For Nursing Practice

Neiva

Borges

Watanabe

et al. 2014

Rev. esc. enferm. USP

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RESUMENEl objetivo del estudio fue caracterizar los mecanismos de daño celular implicado en la fisiopatología de la citotoxicidad de la polimixina B en las células tubulares proximales (LLC-PK1) y discutir las propuestas de intervención de enfermería para identificar a los pacientes de riesgo y considerar la prevención o el tratamiento de la lesión renal aguda nefrotóxica. Corresponde a un estudio experimental cuantitativo in vitro, en el cual las células fueron expuestas a sulfato de polimixina B. La viabilidad celular se determinó por exclusión de los colorantes fluorescentes y el método morfológico con la visualización de cuerpos apoptóticos a la microscopía de fluorescencia. Las células expuestas a polimixina B demostraron reducción de la viabilidad, aumento de célu-las apoptóticas y mayor concentración de la enzima lactato deshidrogenasa. La administración de polimixina B in vitro demostró la necesidad de realizar acciones en la práctica clínica para minimizar los efectos adversos como la nefrotoxicidad. DESCRIPTORESPolimixina B Antibacterianos Lesión renal aguda Células LLC-PK1 Atención de enfermería RESUMOO objetivo do estudo foi caracterizar os mecanismos de lesão celular envolvidos na fisiopatologia da citotoxicidade da polimixina B em células tubulares proximais (LLC-PK1) e discutir as proposições de intervenção do enfermeiro para identificar os pacientes de risco e considerar a prevenção ou o tratamento para lesão renal nefrotóxica. Estudo experimental in vitro, onde as células foram expostas ao sulfato de polimixina B. A viabilidade celular foi determinada pela exclusão dos corantes fluorescentes e o método morfológico com visualização de corpos apoptóticos à microscopia de fluorescência. As células expostas à polimixina B apresentaram redução de viabilidade, aumento do número de células em apoptose e maior concentração da enzima desidrogenase láctea. A administração de polimixina B in vitro demonstrou a necessidade de ações na prática clínica para minimizar os efeitos adversos como a nefrotoxicidade. DESCRITORESPolimixina B Antibacterianos Lesão renal aguda Células LLC-PK1 Cuidados de enfermagem ABSTRACTThe aim of the study was to characterize the cell damage mechanisms involved in the pathophysiology of cytotoxicity of polymyxin B in proximal tubular cells (LLC -PK1) and discuss about the nurses interventions to identify at risk patients and consider prevention or treatment of nephrotoxicity acute kidney injury. This is a quantitative experimental in vitro study, in which the cells were exposed to 375μM polymyxin B sulfate concentration. Cell viability was determined by exclusion of fluorescent dyes and morphological method with visualization of apoptotic bodies for fluorescence microscopy. Cells exposed to polymyxin B showed reduced viability, increased number of apoptotic cells and a higher concentration of the enzyme lactate dehydrogenase. The administration of polymyxin B in vitro showed the need for actions to minimize adverse effects such as nephrotoxicity.

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“…It functions as a support for professional practice and conduction of applied researches (28) . The nurse trained in the development of experimental research seeks contributions to the assistance system and improving the ability to relate pathophysiological mechanisms of drug action and clinical aspects of patient (28)(29) .…”

Section: Experimental Research For Nursingmentioning

confidence: 99%

Instrumental and ethical aspects of experimental research with animal models

Watanabe

Fonseca

Vattimo³

2014

Rev. esc. enferm. USP

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RESUmoOs modelos experimentais com animais oferecem possibilidades de conhecimento da fisiologia, da etiopatogenia das doenças e da ação de medicamentos que estão diretamente relacionados com a assistência de enfermagem de qualidade. Essa revisão integrativa descreve o estado atual dos aspectos instrumentais e éticos da pesquisa experimental com modelos animais, incluindo as principais recomendações dos comitês de ética que visam ao bem-estar animal e faz considerações sobre impacto de seus resultados na enfermagem assistencial. Os dados mostram que, no Brasil, o avanço na ética para o uso de animais para fins científicos consolidou-se com a Lei nº 11.794/2008, que estabelece os procedimentos éticos, atendendo ainda parâ-metros sanitários, genéticos e experimentais. A aplicação da ética no manuseio de animais para fins científicos e didáticos e a obtenção de dados consistentes e de qualidade trazem contribuições inquestionáveis ao enfermeiro, uma vez que oferecem subsídios para se relacionar mecanismos fisiopatológicos e a clínica do paciente.

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Basic sciences and nursing

Cited by 5 publications

References 1 publication

Basic Cycle in Dentistry Students’ Training: The Gap in the Integration of Knowledge and Social Reality

Basic Cycle in Dentistry Students’ Training: The Gap in the Integration of Knowledge and Social Reality

Nephrotoxicity Of Polymyxin B: Experimental Study In Cells And Implications For Nursing Practice

Instrumental and ethical aspects of experimental research with animal models

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