2014
DOI: 10.1590/s0080-623420140000100023
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Abstract: RESUmoOs modelos experimentais com animais oferecem possibilidades de conhecimento da fisiologia, da etiopatogenia das doenças e da ação de medicamentos que estão diretamente relacionados com a assistência de enfermagem de qualidade. Essa revisão integrativa descreve o estado atual dos aspectos instrumentais e éticos da pesquisa experimental com modelos animais, incluindo as principais recomendações dos comitês de ética que visam ao bem-estar animal e faz considerações sobre impacto de seus resultados na enfer… Show more

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Cited by 3 publications
(1 citation statement)
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“…According to the criteria of animal pain judged by the Welfare and Ethical Reference of Experimental Animal Center of Zhejiang University, mild pain manifested as a weight loss of ~5%, only 50-75% of normal intake within 72 h, a small amount of erect hair, normal interactions with other mice, and normal sensitivity to external stimuli ( 11 , 12 ).…”
Section: Methodsmentioning
confidence: 99%
“…According to the criteria of animal pain judged by the Welfare and Ethical Reference of Experimental Animal Center of Zhejiang University, mild pain manifested as a weight loss of ~5%, only 50-75% of normal intake within 72 h, a small amount of erect hair, normal interactions with other mice, and normal sensitivity to external stimuli ( 11 , 12 ).…”
Section: Methodsmentioning
confidence: 99%