Comparative chemical study of MTA and portland cements

Oliveira, Marília Gerhardt de; Xavier, Cristina Braga; Demarco, Flávio Fernando; Pinheiro, Antônio Luis; Costa, Aline Tempel; Pozza, Daniel Humberto

doi:10.1590/s0103-64402007000100002

Cited by 90 publications

(91 citation statements)

References 15 publications

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“…Research data regarding tissue reactions to MTA have demonstrated induction of hard tissue formation (2), bone formation (5), induction of connective tissue formation (6), among others. MTA also presents high chemical similarity to the construction cement known as Portland cement (PC) (7). Considering the economic advantage of PC over MTA, this material is usually included in endodontic investigations.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Cytotoxicity of White MTA, MTA Fillapex® and Portland Cement on Human Periodontal Ligament Fibroblasts

et al. 2013

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The aim of this study was to compare the in vitro cytotoxicity of white mineral trioxide aggregate (MTA), MTA Fillapex ® and Portland cement (PC) on human cultured periodontal ligament fibroblasts. Periodontal ligament fibroblast culture was established and the cells were used for cytotoxic tests after the fourth passage. Cell density was set at 1.25 x10 4 cells/well in 96-well plates. Endodontic material extracts were prepared by placing sealer/ cement specimens (5x3mm) in 1mL of culture medium for 72 h. The extracts were then serially two-fold diluted and inserted into the cell-seeded wells for 24, 48 and 72 h. MTT assay was employed for analysis of cell viability. Cell supernatants were tested for nitric oxide using the Griess reagent system. MTA presented cytotoxic effect in undiluted extracts at 24 and 72 h. MTA Fillapex ® presented the highest cytotoxic levels with important cell viability reduction for pure extracts and at ½ and ¼ dilutions. In this study, PC did not induce alterations in fibroblast viability. Nitric oxide was detected in extract-treated cell supernatants and also in the extracts only, suggesting presence of nitrite in the soluble content of the tested materials. In the present study, MTA Fillapex displayed the highest cytotoxic effect on periodontal ligament fibroblasts followed by white MTA and PC.

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Section: Introductionmentioning

confidence: 99%

In Vitro Cytotoxicity of White MTA, MTA Fillapex® and Portland Cement on Human Periodontal Ligament Fibroblasts

et al. 2013

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“…An alkaline pH and calcium release probably stimulate tissue mineralization (2). The major difference between gray and white MTA (WMTA) is the concentration of iron oxide (FeO).…”

Section: Introductionmentioning

confidence: 99%

L929 cell response to root perforation repair cements: an in vitro cytotoxicity assay

Miranda¹,

Fidel

Boller

2009

Braz. Dent. J.

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This study compared the cytotoxicity of an experimental epoxy-resin and calcium hydroxide-based cement (MBPc), gray mineral trioxide aggregate (MTA) and white mineral trioxide aggregate (WMTA) using the agar overlay method with neutral red dye. L929 cells were seeded into 6-well culture plates where 48-h set test materials were placed on the agar overlay, in triplicate. Teflon and natural rubber served as negative and positive controls. After an incubation period of 24 h at 37ºC in a humidified atmosphere of 5% CO 2 in air, a discolored area around the samples and the positive controls could be observed and measured per quadrant. The mean values were compared and converted into grades to classify the results according to the table of cytotoxicity grades according to the Standard Operating Procedures (SOP) of the Oswaldo Cruz Foundation, Brazil. The nonviable cell areas and the morphological changes in the cells were observed with an inverted microscope. The results showed grade 1 (slight) for the two types of MTA (p>0.05) and grade 2 (mild) for the MBPc (p<0.001). All samples met the requirements of the test as none of the cultures showed reactivity higher than grade 2.

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“…When used in such critical locations, both MTA and Portland cement must withstand compressive forces that could challenge their clinical longevity through time. Other factors affecting porosity such as pore size distributions, microcracks, interface, among others are also important in determining the mechanical properties of cement mate--rials [14,15]. However, porosity which can be semi--empirically and concisely used to describe the relationship between strength and microstructure of porous material is still being studied [16,17].…”

Section: Introduc!onmentioning

confidence: 99%

A gas adsorption porosimetry analysis of Portland cement prepared by compaction vs. compaction with indirect ultrasonic agitation

Azizi

Cubas

Orellana

2014

d3000

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Background: Mineral trioxide aggregate (MTA), is commonly used in endodon9c and re--stora&ve procedures. Objec&ve: Our objec&ve was to introduce gas adsorp&on porosimetry as a viable method for evalua1on of general porosity and specific pore characteris1cs of set Portland cement used in subs1tute for MTA, to inves1gate the effect of two different obtu--ra#on methods (compac#on and compac#on in conjunc#on with indirect ultrasonic agita--!on of the cement paste), and to evaluate the correla.on between the specific pore char--acteris(cs to compressive strength in general. Material and Methods: Portland cement samples were prepared and divided into two groups based on compac4on techniques. An ini#al stereomicroscopic evalua*on was done to assess any differences in appearance of pores randomly selected from either of the two experimental groups. Specific pore charac--teris&cs and compressive strength werequan&fied by a gas adsorp&on porosimeter and an Instron universal tes(ng machine. A two--tailed student t--test was used for sta,s,cal com--parison of data, and a regression analysis was done to evaluate the correla6on between each specific pore characteris-c and compressive strength in general. Results: The gas po--rosimetry method provided measurable values rela2ng to specific pore characteris2cs of Portland cement. The stereomicroscopy evalua6on revealed marked differences between samples from the two groups, namely visibly larger pores both on the outside surface and in cross--sec$ons of specimens prepared by the indirect ultrasonic ac$va$on method. Con--clusions: Gas adsorp*on porosimetry is a feasible method for evalua*on of specific pore characteris)cs of Portland cement and poten)ally other dental materials as well.

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Comparative chemical study of MTA and portland cements

Cited by 90 publications

References 15 publications

In Vitro Cytotoxicity of White MTA, MTA Fillapex® and Portland Cement on Human Periodontal Ligament Fibroblasts

In Vitro Cytotoxicity of White MTA, MTA Fillapex® and Portland Cement on Human Periodontal Ligament Fibroblasts

L929 cell response to root perforation repair cements: an in vitro cytotoxicity assay

A gas adsorption porosimetry analysis of Portland cement prepared by compaction vs. compaction with indirect ultrasonic agitation

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